Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.38 |
| ▸ | MAP3K5 | Q99683 | 3/20 | 0.36 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.33 |
| ▸ | MTOR | P42345 | 2/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
| ▸ | LYN | P07948 | 1/20 | 0.32 |
| ▸ | HCK | P08631 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | FRK | P42685 | 1/20 | 0.32 |
| ▸ | BLK | P51451 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20648909 | 1.00 | TRPV4 (0.38) | TRPV4MAP3K5TNIKMCHR1ABL1 | |
| SCHEMBL20649188 | 0.91 | MAP3K5 (0.37) | MAP3K5TNIKABL1RIN1POLB | |
| SCHEMBL20648898 | 0.91 | MAP3K5 (0.37) | MAP3K5TNIKABL1RIN1POLB | |
| SCHEMBL20649017 | 0.89 | TRPV4 (0.38) | TRPV4MAP3K5TNIKMCHR1ABL1 | |
| SCHEMBL20648905 | 0.89 | TRPV4 (0.38) | TRPV4MAP3K5TNIKMCHR1ABL1 | |
| SCHEMBL20648877 | 0.82 | MAPT (0.34) | MAP3K5MCHR1ABL1RIN1POLB | |
| SCHEMBL20648884 | 0.81 | MAP3K5 (0.37) | MAP3K5ABL1RIN1POLB | |
| SCHEMBL20648904 | 0.80 | MAP3K5 (0.37) | MAP3K5TNIKABL1RIN1POLB | |
| SCHEMBL20649215 | 0.79 | MAP3K5 (0.46) | MAP3K5ABL1RIN1POLB | |
| SCHEMBL20648776 | 0.79 | MAP3K5 (0.39) | MAP3K5ABL1RIN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019013789-A1 | ANTIMICROBIAL COMPOUNDS | CURZA GLOBAL, LLC (US) | 2019-01-17 | — | — | WO | disclosed |