Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K5 | Q99683 | 5/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.35 |
| ▸ | TNIK | Q9UKE5 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SUV39H1 | O43463 | 1/20 | 0.31 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.31 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.31 |
| ▸ | HTR1F | P30939 | 1/20 | 0.31 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | FLT3 | P36888 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20648898 | 1.00 | MAP3K5 (0.37) | MAP3K5ABL1RIN1TNIKL3MBTL1 | |
| SCHEMBL20648909 | 0.91 | TRPV4 (0.38) | MAP3K5ABL1RIN1TNIKPOLB | |
| SCHEMBL20649283 | 0.91 | TRPV4 (0.38) | MAP3K5ABL1RIN1TNIKPOLB | |
| SCHEMBL20648904 | 0.89 | MAP3K5 (0.37) | MAP3K5ABL1RIN1TNIKL3MBTL1 | |
| SCHEMBL20648844 | 0.87 | KDM1A (0.34) | MAP3K5ABL1RIN1L3MBTL1POLB | |
| SCHEMBL20648884 | 0.85 | MAP3K5 (0.37) | MAP3K5ABL1RIN1POLBLMNA | |
| SCHEMBL20649248 | 0.82 | QPCT (0.37) | MAP3K5ABL1RIN1POLBHTR1F | |
| SCHEMBL20648913 | 0.82 | QPCT (0.37) | MAP3K5ABL1RIN1POLBHTR1F | |
| SCHEMBL20649215 | 0.81 | MAP3K5 (0.46) | MAP3K5ABL1RIN1POLB | |
| SCHEMBL20648776 | 0.81 | MAP3K5 (0.39) | MAP3K5ABL1RIN1POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019013789-A1 | ANTIMICROBIAL COMPOUNDS | CURZA GLOBAL, LLC (US) | 2019-01-17 | — | — | WO | disclosed |