SCHEMBL20650495

SCHEMBL20650495

Cc1ccc(N(I)c2cccc3c2oc2c(C(F)(F)F)cccc23)c(C)c1

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 1/20 0.33
NR1H3 Q13133 1/20 0.33
ELANE P08246 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20650258 0.89
SCHEMBL20650125 0.87 ELANE (0.33) ELANE
SCHEMBL21020293 0.86 NR1H2 (0.34) NR1H2NR1H3ELANE
SCHEMBL20650705 0.84 PTGER1 (0.32)
SCHEMBL20650814 0.84 CYP1A2 (0.31)
SCHEMBL20650503 0.82 KIF11 (0.34)
SCHEMBL20650772 0.80 LMNA (0.39)
SCHEMBL20650124 0.80 KIF11 (0.31)
SCHEMBL20650423 0.80 ELANE (0.33) ELANE
SCHEMBL20650351 0.79 LMNA (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3428152-B1 COMPOUND AND ORGANIC ELECTRONIC ELEMENT COMPRISING SAME LG CHEMICAL LTD (KR) 2021-11-03 EP disclosed
EP-3428152-A1 COMPOUND AND ORGANIC ELECTRONIC ELEMENT COMPRISING SAME LG Chem, Ltd. (KR) 2019-01-16 EP disclosed