SCHEMBL20650710

SCHEMBL20650710

Fc1ccc(N(I)c2cccc3c2oc2c(C(F)(F)F)cccc23)cc1

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 1/20 0.31
NR1H3 Q13133 1/20 0.31
EPHX2 P34913 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20650505 0.89 EPHX2 (0.40) EPHX2
SCHEMBL23967743 0.88
SCHEMBL20650705 0.88 PTGER1 (0.32)
SCHEMBL20650707 0.87 EPHX2 (0.32) EPHX2
SCHEMBL23967717 0.86 EPHX2 (0.33) EPHX2
SCHEMBL20650704 0.85 S1PR1 (0.31)
SCHEMBL20650709 0.85 P2RX7 (0.31)
SCHEMBL20650699 0.85 SLC22A12 (0.33)
SCHEMBL20650502 0.85 P2RY1 (0.33) EPHX2
SCHEMBL21020302 0.84 NR1H2 (0.33) NR1H2NR1H3EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3428152-A1 COMPOUND AND ORGANIC ELECTRONIC ELEMENT COMPRISING SAME LG Chem, Ltd. (KR) 2019-01-16 EP disclosed