SCHEMBL20650699

SCHEMBL20650699

N#Cc1ccc(N(I)c2cccc3c2oc2c(C(F)(F)F)cccc23)cc1

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SLC22A12 Q96S37 1/20 0.33
TDO2 P48775 1/20 0.33
KIF11 P52732 2/20 0.33
CNR2 P34972 1/20 0.32
USP1 O94782 1/20 0.31
WDR48 Q8TAF3 1/20 0.31
CYP19A1 P11511 2/20 0.30
HSD11B1 P28845 1/20 0.30
TRPV1 Q8NER1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20650451 0.88 KIF11 (0.31) KIF11
SCHEMBL21020296 0.85 ABCG2 (0.36) SLC22A12KIF11CNR2USP1WDR48
SCHEMBL23967781 0.85 KIF11 (0.33) KIF11
SCHEMBL20650710 0.85 NR1H2 (0.31)
SCHEMBL20650505 0.85 EPHX2 (0.40)
SCHEMBL20650705 0.84 PTGER1 (0.32)
SCHEMBL20650355 0.84 AR (0.34)
SCHEMBL20650707 0.82 EPHX2 (0.32)
SCHEMBL20650765 0.82 KDM4E (0.33)
SCHEMBL23967717 0.81 EPHX2 (0.33) HSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3428152-A1 COMPOUND AND ORGANIC ELECTRONIC ELEMENT COMPRISING SAME LG Chem, Ltd. (KR) 2019-01-16 EP disclosed