SCHEMBL20650718

SCHEMBL20650718

CCc1cccc2c1oc1c(N(I)c3ccccc3)cccc12

nearest known ligand 0.35

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.35
GABRA1 P14867 2/20 0.33
GABRB2 P47870 2/20 0.33
KDM1A O60341 1/20 0.33
GLA P06280 1/20 0.33
STING1 Q86WV6 1/20 0.33
SLC11A2 P49281 1/20 0.33
TP53 P04637 1/20 0.33
LMNA P02545 1/20 0.32
GAA P10253 1/20 0.32
MAPT P10636 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
KDM4E B2RXH2 1/20 0.31
SIGMAR1 Q99720 1/20 0.31
CYP2D6 P10635 1/20 0.31
PTGER1 P34995 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20650250 0.88 SLC11A2 (0.31) ALOX5GABRA1GABRB2SLC11A2
SCHEMBL20650408 0.85 TNKS (0.33) SLC11A2NPSR1
SCHEMBL20650252 0.85 SLC11A2 (0.30) SLC11A2
SCHEMBL20650409 0.85 LMNA (0.34) SLC11A2LMNASIGMAR1CYP2D6
SCHEMBL20650254 0.84 CYP2A6 (0.33)
SCHEMBL20650366 0.84 PTGER1 (0.35) CYP2D6PTGER1
SCHEMBL21020438 0.84 ALOX5 (0.36) ALOX5GABRA1GABRB2KDM1AGLA
SCHEMBL20650319 0.83 ALOX5 (0.34) ALOX5GABRA1GABRB2SLC11A2LMNA
SCHEMBL20649835 0.81 ALOX5 (0.33) ALOX5GABRA1GABRB2SLC11A2SIGMAR1
SCHEMBL20650419 0.81 MCL1 (0.40) SMN1; SMN2SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3428152-A1 COMPOUND AND ORGANIC ELECTRONIC ELEMENT COMPRISING SAME LG Chem, Ltd. (KR) 2019-01-16 EP disclosed