SCHEMBL20650780

SCHEMBL20650780

Cc1cccc2c1oc1c(N(I)c3ccc(C(C)C)cc3)cccc12

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 1/20 0.33
TNKS O95271 1/20 0.32
PARP1 P09874 1/20 0.32
TNKS2 Q9H2K2 1/20 0.32
HDAC6 Q9UBN7 1/20 0.32
PARP2 Q9UGN5 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20650160 0.86 TNKS (0.35) TNKSPARP1TNKS2HDAC6PARP2
SCHEMBL20650725 0.85 TNKS (0.32) TNKSPARP1TNKS2HDAC6PARP2
SCHEMBL21021025 0.85 DHFR (0.34) MCL1TNKSPARP1TNKS2HDAC6
SCHEMBL20650419 0.84 MCL1 (0.40) MCL1
SCHEMBL20649814 0.84 TNKS (0.40) TNKSPARP1TNKS2HDAC6PARP2
SCHEMBL20650300 0.83 MCL1 (0.34) MCL1
SCHEMBL20650408 0.83 TNKS (0.33) TNKSPARP1TNKS2HDAC6PARP2
SCHEMBL20650391 0.83 TNKS (0.30) TNKSPARP1TNKS2HDAC6PARP2
SCHEMBL20650298 0.82 MCL1 (0.33) MCL1
SCHEMBL23967895 0.82 ALDH1A1 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3428152-B1 COMPOUND AND ORGANIC ELECTRONIC ELEMENT COMPRISING SAME LG CHEMICAL LTD (KR) 2021-11-03 EP disclosed
EP-3428152-A1 COMPOUND AND ORGANIC ELECTRONIC ELEMENT COMPRISING SAME LG Chem, Ltd. (KR) 2019-01-16 EP disclosed