SCHEMBL20650792

SCHEMBL20650792

Fc1ccc(N(I)c2cccc3c2sc2ccccc23)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.38
GPR3 P46089 1/20 0.37
ALOX5 P09917 1/20 0.35
THRB P10828 1/20 0.34
CYP2D6 P10635 1/20 0.33
CHRM1 P11229 1/20 0.33
HTR2A P28223 1/20 0.33
HRH1 P35367 1/20 0.33
PTGS2 P35354 1/20 0.33
PARP14 Q460N5 1/20 0.33
RAB9A P51151 4/20 0.33
MAPT P10636 4/20 0.33
ALDH1A1 P00352 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
HPGD P15428 1/20 0.33
LIMK1 P53667 1/20 0.32
CDK5 Q00535 1/20 0.32
CDK5R1 Q15078 1/20 0.32
PMM2 O15305 1/20 0.31
MPI P34949 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20650287 0.88 GPR3 (0.42) IDO1GPR3ALOX5PARP14RAB9A
SCHEMBL20650283 0.85 ALOX5 (0.40) GPR3ALOX5PARP14RAB9AMAPT
SCHEMBL20650775 0.85 MPI (0.35) GPR3ALOX5PARP14RAB9AMAPT
SCHEMBL20650309 0.84
SCHEMBL21020583 0.82 HRH1 (0.39) IDO1GPR3ALOX5THRBCYP2D6
SCHEMBL20650796 0.82 GPR3 (0.39) GPR3ALOX5CYP2D6CHRM1HRH1
SCHEMBL20650788 0.82 GPR3 (0.34) GPR3ALOX5PARP14RAB9AMAPT
SCHEMBL20650794 0.82 MAPT (0.35) GPR3ALOX5PARP14RAB9AMAPT
SCHEMBL20650466 0.82 GPR3 (0.34) GPR3ALOX5CYP2D6CHRM1HRH1
SCHEMBL20649622 0.81 MEN1 (0.32) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3428152-A1 COMPOUND AND ORGANIC ELECTRONIC ELEMENT COMPRISING SAME LG Chem, Ltd. (KR) 2019-01-16 EP disclosed