Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 2/20 | 0.36 |
| ▸ | STK17B | O94768 | 1/20 | 0.33 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20640575 | 0.83 | STK17B (0.37) | CRHR1STK17BSTK17A | |
| SCHEMBL20640650 | 0.81 | STK17B (0.34) | CRHR1STK17BSTK17A | |
| SCHEMBL1935476 | 0.76 | KDM4E (0.45) | CRHR1STK17BSTK17A | |
| SCHEMBL20652358 | 0.72 | CRHR1 (0.48) | CRHR1STK17BSTK17A | |
| SCHEMBL13649023 | 0.70 | MEN1 (0.40) | CRHR1 | |
| SCHEMBL20652181 | 0.69 | STK17B (0.39) | STK17BSTK17A | |
| SCHEMBL20640705 | 0.69 | CRHR1 (0.34) | CRHR1STK17BSTK17A | |
| SCHEMBL1937566 | 0.68 | STK17B (0.36) | CRHR1STK17BSTK17A | |
| SCHEMBL20640580 | 0.68 | CRHR1 (0.39) | CRHR1STK17BSTK17A | |
| SCHEMBL1937589 | 0.67 | KDM4E (0.45) | CRHR1STK17BSTK17A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019012093-A1 | INHIBITORS OF LEUCINE RICH REPEAT KINASE 2 | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2019-01-17 | — | — | WO | disclosed |