Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STK17B | O94768 | 1/20 | 0.39 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20652182 | 0.80 | STK17B (0.40) | STK17BSTK17AALDH1A1L3MBTL1 | |
| SCHEMBL20640564 | 0.77 | ALDH1A1 (0.41) | STK17BSTK17AALDH1A1L3MBTL1 | |
| SCHEMBL20652230 | 0.77 | STK17A (0.42) | STK17BSTK17AALDH1A1L3MBTL1 | |
| SCHEMBL1935123 | 0.77 | ALDH1A1 (0.41) | STK17BSTK17AALDH1A1L3MBTL1 | |
| SCHEMBL1937307 | 0.74 | ESR1 (0.49) | STK17BSTK17AALDH1A1L3MBTL1 | |
| SCHEMBL1937173 | 0.70 | STK17A (0.41) | STK17BSTK17AALDH1A1L3MBTL1 | |
| SCHEMBL20652190 | 0.69 | CRHR1 (0.36) | STK17BSTK17A | |
| SCHEMBL1935303 | 0.68 | STK17B (0.47) | STK17BSTK17AALDH1A1L3MBTL1 | |
| SCHEMBL1934538 | 0.66 | STK17A (0.51) | STK17BSTK17AALDH1A1L3MBTL1 | |
| SCHEMBL1938676 | 0.65 | STK17A (0.51) | STK17BSTK17AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019012093-A1 | INHIBITORS OF LEUCINE RICH REPEAT KINASE 2 | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2019-01-17 | — | — | WO | disclosed |