SCHEMBL2065286

SCHEMBL2065286

CCc1nc2cccnn2c1S(=O)(=O)Cl

nearest known ligand 0.40

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PDE4A P27815 17/20 0.40
PDE4B Q07343 17/20 0.38
PDE4D Q08499 17/20 0.38
PDE4C Q08493 16/20 0.38
KLK7 P49862 1/20 0.33
DYRK1A Q13627 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2066548 0.89 PDE4A (0.39) PDE4APDE4BPDE4DPDE4CKLK7
SCHEMBL2066954 0.85 PDE4A (0.40) PDE4APDE4BPDE4DPDE4CKLK7
SCHEMBL2066389 0.81 PDE4A (0.39) PDE4APDE4BPDE4DPDE4CKLK7
SCHEMBL2066681 0.80 PDE4A (0.40) PDE4APDE4BPDE4DPDE4CKLK7
SCHEMBL2067978 0.78 PDE4A (0.36) PDE4APDE4BPDE4DPDE4CKLK7
SCHEMBL2067969 0.77 PDE4B (0.35) PDE4APDE4BPDE4DPDE4C
SCHEMBL2068562 0.77 PDE4B (0.35) PDE4APDE4BPDE4DPDE4CKLK7
SCHEMBL2066599 0.77 PDE4A (0.37) PDE4APDE4BPDE4DPDE4CKLK7
SCHEMBL13080991 0.76 PDE4A (0.41) PDE4APDE4BPDE4DPDE4C
SCHEMBL14754859 0.76 PDE4A (0.47) PDE4APDE4BPDE4DPDE4CDYRK1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8148524-B2 Process for producing sulfonyl chloride compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-04-03 US disclosed
EP-1932846-B1 METHOD FOR PRODUCING SULFONYL CHLORIDE COMPOUND SUMITOMO CHEMICAL CO (JP) 2010-10-27 EP disclosed
US-20090247748-A1 PROCESS FOR PRODUCING SULFONYL CHLORIDE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-10-01 US disclosed
EP-1932846-A1 METHOD FOR PRODUCING SULFONYL CHLORIDE COMPOUND Sumitomo Chemical Company, Limited (JP) 2008-06-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090247748-A1 PROCESS FOR PRODUCING SULFONYL CHLORIDE COMPOUND SALL4, CLCN2, CLIC1 PDE4A 4317/4885PDE4B 4162/4885PDE4D 4596/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.