SCHEMBL2067969

SCHEMBL2067969

O=S(=O)(Cl)c1c(F)nc2cccnn12

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PDE4B Q07343 19/20 0.35
PDE4D Q08499 19/20 0.35
PDE4A P27815 18/20 0.35
PDE4C Q08493 18/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2065831 0.84 CA1 (0.36) PDE4BPDE4DPDE4APDE4C
SCHEMBL2067978 0.82 PDE4A (0.36) PDE4BPDE4DPDE4APDE4C
SCHEMBL2066681 0.81 PDE4A (0.40) PDE4BPDE4DPDE4APDE4C
SCHEMBL2068562 0.81 PDE4B (0.35) PDE4BPDE4DPDE4APDE4C
SCHEMBL2065286 0.77 PDE4A (0.40) PDE4BPDE4DPDE4APDE4C
SCHEMBL2066431 0.77 PDE4A (0.33) PDE4BPDE4DPDE4APDE4C
SCHEMBL2066599 0.77 PDE4A (0.37) PDE4BPDE4DPDE4APDE4C
SCHEMBL2066955 0.76 PDE4A (0.42) PDE4BPDE4DPDE4APDE4C
SCHEMBL2066389 0.76 PDE4A (0.39) PDE4BPDE4DPDE4APDE4C
SCHEMBL2066548 0.75 PDE4A (0.39) PDE4BPDE4DPDE4APDE4C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8148524-B2 Process for producing sulfonyl chloride compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-04-03 US disclosed
EP-1932846-B1 METHOD FOR PRODUCING SULFONYL CHLORIDE COMPOUND SUMITOMO CHEMICAL CO (JP) 2010-10-27 EP disclosed
US-20090247748-A1 PROCESS FOR PRODUCING SULFONYL CHLORIDE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-10-01 US disclosed
EP-1932846-A1 METHOD FOR PRODUCING SULFONYL CHLORIDE COMPOUND Sumitomo Chemical Company, Limited (JP) 2008-06-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090247748-A1 PROCESS FOR PRODUCING SULFONYL CHLORIDE COMPOUND SALL4, CLCN2, CLIC1 PDE4B 4162/4885PDE4D 4596/4885PDE4A 4317/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.