Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25415568 | 0.85 | KDM4E (0.43) | ALDH1A1CYP3A4CYP2C9CYP2C19TDP1 | |
| SCHEMBL9289298 | 0.85 | TP53 (0.42) | ALDH1A1CYP3A4CYP2C9CYP2C19TDP1 | |
| SCHEMBL7923729 | 0.83 | TAAR1 (0.52) | ALDH1A1ALOX15KCNH2 | |
| SCHEMBL10705258 | 0.81 | TDP1 (0.44) | ALDH1A1TDP1KDM4EMAPTHTT | |
| SCHEMBL27705430 | 0.80 | ALDH1A1 (0.39) | ALDH1A1CYP3A4CYP2C9CYP2C19TDP1 | |
| SCHEMBL20221303 | 0.79 | NPC1 (0.47) | TDP1MAPTHTTNPSR1NPC1 | |
| SCHEMBL1634907 | 0.78 | ALDH1A1 (0.46) | ALDH1A1CYP3A4CYP2C9CYP2C19TDP1 | |
| SCHEMBL27781873 | 0.78 | ALDH1A1 (0.37) | ALDH1A1CYP3A4CYP2C9CYP2C19TDP1 | |
| SCHEMBL27611446 | 0.78 | NPC1 (0.50) | NPC1RAB9AKCNH2 | |
| SCHEMBL11021723 | 0.76 | KDM4E (0.36) | ALDH1A1CYP3A4CYP2C9CYP2C19TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120255898-A1 | SEMIPERMEABLE POLYMERS AND METHOD FOR PRODUCING SAME | ELTRON RESEARCH & DEVELOPMENT, INC. (US) | 2012-10-11 | — | — | US | disclosed |
| US-8147735-B2 | Semipermeable polymers and method for producing same | ELTRON RESEARCH & DEVELOPMENT, INC. (US) | 2012-04-03 | — | — | US | disclosed |
| WO-2010042250-A2 | SEMIPERMEABLE POLYMERS AND METHOD FOR PRODUCING SAME | ELTRON RESEARCH AND DEVELOPMENT, INC. (US) | 2010-04-15 | — | — | WO | disclosed |
| US-20100006495-A1 | SEMIPERMEABLE POLYMERS AND METHOD FOR PRODUCING SAME | ELTRON RESEARCH AND DEVELOPMENT, INC. (US) | 2010-01-14 | — | — | US | disclosed |