SCHEMBL7923729

SCHEMBL7923729

FN(CCc1ccccc1)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.52
AOC3 Q16853 4/20 0.48
KCNH2 Q12809 3/20 0.46
CHRM2 P08172 1/20 0.45
HTR1A P08908 1/20 0.45
ADRA2A P08913 1/20 0.45
CHRM1 P11229 1/20 0.45
DRD1 P21728 1/20 0.45
SLC6A2 P23975 1/20 0.45
SLC6A4 P31645 1/20 0.45
ADRA1A P35348 1/20 0.45
OPRM1 P35372 1/20 0.45
DRD3 P35462 1/20 0.45
SLC6A3 Q01959 1/20 0.45
SIGMAR1 Q99720 4/20 0.44
ALDH1A1 P00352 1/20 0.42
HPGD P15428 1/20 0.42
ALOX15 P16050 1/20 0.42
ALOX12 P18054 1/20 0.42
CASP1 P29466 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2065327 0.83 ALDH1A1 (0.40) KCNH2ALDH1A1ALOX15
SCHEMBL1467598 0.78 TAAR1 (0.58) TAAR1AOC3KCNH2CHRM2HTR1A
Bromide SCHEMBL6906995 0.76 TAAR1 (0.56) TAAR1AOC3KCNH2CHRM2HTR1A
SCHEMBL11513213 0.76 TSHR (0.50) TAAR1AOC3ALDH1A1
SCHEMBL3006764 0.76 TAAR1 (0.56) TAAR1AOC3KCNH2CHRM2HTR1A
SCHEMBL8071666 0.76 KCNH2 (0.64) TAAR1AOC3KCNH2CHRM2HTR1A
SCHEMBL18227028 0.75 TAAR1 (0.45) TAAR1AOC3SIGMAR1ALDH1A1
SCHEMBL25415568 0.74 KDM4E (0.43) OPRM1ALDH1A1
Hydrochloric Acid SCHEMBL11791734 0.74 KCNH2 (0.62) TAAR1AOC3KCNH2CHRM2HTR1A
SCHEMBL9289298 0.74 TP53 (0.42) KCNH2CHRM2HTR1AADRA2ACHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6222073-B1 REACTING AROMATIC OLEFIN WITH ANILINE COMPOUND IN INERT SOLVENT IN PRESENCE OF BASIC CATALYST SELECTED FROM ALKALI METAL OR ALKALINE EARTH METAL ALCOHOLATES, ALKALI METAL OR ALKALINE EARTH METAL AMIDES TO FORM N-ALKYLATED ANILINES AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO. KG (DE) 2001-04-24 US disclosed