SCHEMBL20654094

SCHEMBL20654094

O=P(c1ccccc1)(c1ccccc1)c1cccc(P(=O)(c2ccccc2)c2ccccc2)c1-c1cccc(-c2ccccc2)n1

nearest known ligand 0.53

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
RAB9A P51151 1/20 0.53
ASIC3 Q9UHC3 1/20 0.42
SMO Q99835 1/20 0.40
NPSR1 Q6W5P4 2/20 0.40
TOP1 P11387 1/20 0.39
HTT P42858 3/20 0.37
RECQL P46063 1/20 0.37
ALDH1A1 P00352 3/20 0.36
POLB P06746 2/20 0.36
MAPT P10636 3/20 0.36
HPGD P15428 1/20 0.36
HSD17B10 Q99714 1/20 0.36
KAT6A Q92794 2/20 0.35
CNR1 P21554 1/20 0.35
ADORA3 P0DMS8 1/20 0.33
KDM4E B2RXH2 1/20 0.33
CYP2A6 P11509 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20654236 0.85 TOP1 (0.43) MEN1KMT2ARAB9ANPSR1TOP1
SCHEMBL20654182 0.85 MEN1 (0.52) MEN1KMT2ARAB9AASIC3SMO
SCHEMBL20654093 0.82 TOP1 (0.43) MEN1KMT2ANPSR1TOP1HTT
SCHEMBL13171437 0.80 MEN1 (0.58) MEN1KMT2ARAB9AASIC3SMO
SCHEMBL20654154 0.79 KDM4E (0.45) MEN1KMT2ARAB9ANPSR1HTT
SCHEMBL238685 0.79 PARP1 (0.51) MEN1KMT2ARAB9AASIC3NPSR1
SCHEMBL14020795 0.78 NPSR1 (0.52) MEN1KMT2ANPSR1HTTALDH1A1
SCHEMBL20654226 0.78 HSD17B1 (0.38) MEN1KMT2ARAB9ANPSR1TOP1
SCHEMBL20654135 0.77 NPSR1 (0.42) MEN1KMT2ARAB9ANPSR1TOP1
SCHEMBL11991100 0.77 MEN1 (0.54) MEN1KMT2ARAB9AASIC3SMO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10727415-B2 Phosphine-based compound and organic electroluminescence device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2020-07-28 US disclosed
US-20190019959-A1 PHOSPHINE-BASED COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2019-01-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10727415-B2 Phosphine-based compound and organic electroluminescence device including the same PHOSPHO1, PEF1, ODC1 MEN1 207/4885KMT2A 849/4885RAB9A 1102/4885
US-20190019959-A1 PHOSPHINE-BASED COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME PHOSPHO1, PEF1, ODC1 MEN1 207/4885KMT2A 849/4885RAB9A 1102/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.