Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 13/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.37 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.37 |
| ▸ | PDE1A | P54750 | 1/20 | 0.37 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.37 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20652795 | 0.93 | P2RX3 (0.47) | P2RX3MAPK1POLBHIF1AALDH1A1 | |
| SCHEMBL20652797 | 0.93 | HIF1A (0.46) | P2RX3LMNAMAPK1POLBHIF1A | |
| SCHEMBL22105587 | 0.81 | P2RX3 (0.47) | P2RX3LMNAMAPK1POLBHIF1A | |
| SCHEMBL22105580 | 0.81 | LMNA (0.49) | P2RX3LMNAMAPK1POLBHIF1A | |
| SCHEMBL20655939 | 0.80 | P2RX3 (0.43) | P2RX3LMNAMAPK1 | |
| SCHEMBL20652775 | 0.76 | P2RX3 (0.45) | P2RX3LMNAMAPK1HIF1AALDH1A1 | |
| SCHEMBL20652978 | 0.76 | P2RX3 (0.47) | P2RX3NPSR1 | |
| SCHEMBL20653064 | 0.76 | P2RX3 (0.44) | P2RX3LMNAMAPK1HIF1AALDH1A1 | |
| SCHEMBL20653062 | 0.75 | P2RX3 (0.46) | P2RX3LMNAALDH1A1NPSR1 | |
| SCHEMBL24095610 | 0.73 | P2RX3 (0.42) | P2RX3LMNAMAPK1HIF1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019011802-A1 | NOVEL SUBSTITUTED XANTHINE DERIVATIVES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2019-01-17 | — | — | WO | disclosed |