Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CYP26A1 | O43174 | 3/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | RXRB | P28702 | 1/20 | 0.32 |
| ▸ | RXRG | P48443 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.30 |
| ▸ | RGS12 | O14924 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3868774 | 0.88 | MAPT (0.38) | CA5ACYP26A1PTPN1RXRARXRB | |
| SCHEMBL3868703 | 0.84 | MAPT (0.39) | CA5ACYP26A1PTPN1RXRARXRB | |
| SCHEMBL14451061 | 0.82 | PTPN1 (0.31) | PTPN1 | |
| SCHEMBL8116380 | 0.82 | PTPN1 (0.33) | PTPN1 | |
| SCHEMBL12952231 | 0.82 | ADRB2 (0.32) | PTPN1ALDH1A1CYP26B1 | |
| SCHEMBL857034 | 0.81 | PTPN1 (0.33) | PTPN1LMNATDP1 | |
| SCHEMBL2065361 | 0.81 | ALDH1A1 (0.31) | PTPN1ALDH1A1CYP26B1 | |
| SCHEMBL1080138 | 0.81 | PTPN1 (0.33) | PTPN1 | |
| SCHEMBL7606803 | 0.80 | KMT2A (0.35) | KDM4EMAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL3873489 | 0.80 | MAPT (0.40) | CA5ACYP26A1RXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8148539-B2 | Cyanine dye labelling reagents | GE HEALTHCARE UK LIMITED (GB) | 2012-04-03 | — | — | US | disclosed |
| US-8148539-B2 | Cyanine dye labelling reagents | GE HEALTHCARE UK LIMITED (GB) | 2012-04-03 | — | — | US | disclosed |
| US-8148539-B2 | Cyanine dye labelling reagents | GE HEALTHCARE UK LIMITED (GB) | 2012-04-03 | — | — | US | disclosed |
| EP-1678258-B1 | CYANINE DYE LABELLING REAGENTS | GE HEALTHCARE LTD (GB) | 2011-08-31 | — | — | EP | disclosed |
| EP-2360211-A1 | Fluorescently-labelled target components | GE Healthcare Limited (GB) | 2011-08-24 | — | — | EP | disclosed |
| US-20100267937-A1 | Cyanine Dye Labelling Reagents | WEST RICHARD M | 2010-10-21 | — | — | US | disclosed |
| US-20100267937-A1 | Cyanine Dye Labelling Reagents | WEST RICHARD M | 2010-10-21 | — | — | US | disclosed |
| US-20100267937-A1 | Cyanine Dye Labelling Reagents | WEST RICHARD M | 2010-10-21 | — | — | US | disclosed |
| US-7750163-B2 | Cyanine dye labelling reagents | GE Healthcare U.K. Limited (GB) | 2010-07-06 | — | — | US | disclosed |
| US-7750163-B2 | Cyanine dye labelling reagents | GE Healthcare U.K. Limited (GB) | 2010-07-06 | — | — | US | disclosed |
| US-7750163-B2 | Cyanine dye labelling reagents | GE Healthcare U.K. Limited (GB) | 2010-07-06 | — | — | US | disclosed |
| US-20070203343-A1 | Cyanine Dye Labelling Reagents | GE HEALTHCARE UK LIMITED (GB) | 2007-08-30 | — | — | US | disclosed |
| US-20070203343-A1 | Cyanine Dye Labelling Reagents | GE HEALTHCARE UK LIMITED (GB) | 2007-08-30 | — | — | US | disclosed |
| US-20070203343-A1 | Cyanine Dye Labelling Reagents | GE HEALTHCARE UK LIMITED (GB) | 2007-08-30 | — | — | US | disclosed |
| EP-1678258-A1 | CYANINE DYE LABELLING REAGENTS | GE Healthcare Limited (GB) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005044923-A1 | CYANINE DYE LABELLING REAGENTS | GE HEALTHCARE LIMITED (GB) | 2005-05-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070203343-A1 | Cyanine Dye Labelling Reagents | IK, H1-5, H1-3 | CA5A 3515/4885CYP26A1 4218/4885PTPN1 3323/4885 |
| US-20100267937-A1 | Cyanine Dye Labelling Reagents | IK, H1-5, H1-3 | CA5A 3441/4885CYP26A1 4289/4885PTPN1 3312/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.