SCHEMBL20656715

SCHEMBL20656715

CC1=C(C)C(C)C([Si](C)(C)C2C=Cc3c(-c4ccccc4)cccc32)=C1C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20656713 0.90
SCHEMBL20656716 0.80
SCHEMBL16669020 0.78
SCHEMBL6671909 0.78 BRD4 (0.32)
SCHEMBL7870640 0.77 ADRA2A (0.33)
SCHEMBL16669069 0.74
SCHEMBL20972487 0.73 CYP2A6 (0.32)
SCHEMBL29767618 0.73 CYP2A6 (0.32)
SCHEMBL15863721 0.72
SCHEMBL6675584 0.71 GPR3 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10995167-B2 Metallocene compound, catalyst component for olefin polymerization and catalyst for olefin polymerization containing the same, and method for producing olefin polymer using catalyst for olefin polymerization JAPAN POLYETHYLENE CORPORATION (JP) 2021-05-04 US disclosed
EP-3431483-B1 METALLOCENE COMPOUND, CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND CATALYST FOR OLEFIN POLYMERIZATION CONTAINING THE SAME, AND METHOD FOR PRODUCING OLEFIN POLYMER USING CATALYST FOR OLEFIN POLYMERIZATION CATALYST JAPAN POLYETHYLENE CORP (JP) 2021-03-03 EP disclosed
US-20190092887-A1 METALLOCENE COMPOUND, CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND CATALYST FOR OLEFIN POLYMERIZATION CONTAINING THE SAME, AND METHOD FOR PRODUCING OLEFIN POLYMER USING CATALYST FOR OLEFIN POLYMERIZATION JAPAN POLYETHYLENE CORPORATION (JP) 2019-03-28 US disclosed
EP-3431483-A1 METALLOCENE COMPOUND, OLEFIN POLYMERIZATION CATALYST COMPONENT AND OLEFIN POLYMERIZATION CATALYST EACH COMPRISING SAME, AND METHOD FOR PRODUCING OLEFIN POLYMER USING SAID OLEFIN POLYMERIZATION CATALYST Japan Polyethylene Corporation (JP) 2019-01-23 EP disclosed