Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.71 |
| ▸ | THRB | P10828 | 1/20 | 0.71 |
| ▸ | MAPT | P10636 | 6/20 | 0.67 |
| ▸ | MEN1 | O00255 | 6/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.67 |
| ▸ | LMNA | P02545 | 3/20 | 0.67 |
| ▸ | TP53 | P04637 | 2/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | RECQL | P46063 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.65 |
| ▸ | NPC1 | O15118 | 1/20 | 0.65 |
| ▸ | RAB9A | P51151 | 1/20 | 0.65 |
| ▸ | F13A1 | P00488 | 2/20 | 0.63 |
| ▸ | TGM2 | P21980 | 2/20 | 0.63 |
| ▸ | TGM1 | P22735 | 2/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | NAMPT | P43490 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13212144 | 1.00 | ALDH1A1 (0.71) | ALDH1A1THRBMAPTMEN1KMT2A | |
| SCHEMBL20657301 | 0.99 | ALDH1A1 (0.73) | ALDH1A1THRBMAPTMEN1KMT2A | |
| SCHEMBL20657300 | 0.99 | ALDH1A1 (0.73) | ALDH1A1THRBMAPTMEN1KMT2A | |
| SCHEMBL20670978 | 0.89 | ALDH1A1 (0.63) | ALDH1A1THRBMAPTMEN1KMT2A | |
| SCHEMBL29931065 | 0.89 | ALDH1A1 (0.63) | ALDH1A1THRBMAPTMEN1KMT2A | |
| SCHEMBL21772376 | 0.89 | ALDH1A1 (0.63) | ALDH1A1THRBMAPTMEN1KMT2A | |
| SCHEMBL20657354 | 0.88 | CYP1A2 (0.65) | ALDH1A1THRBMAPTMEN1KMT2A | |
| SCHEMBL20657308 | 0.88 | ALDH1A1 (0.65) | ALDH1A1THRBMAPTMEN1KMT2A | |
| SCHEMBL20669428 | 0.88 | ALDH1A1 (0.65) | ALDH1A1THRBMAPTMEN1KMT2A | |
| SCHEMBL20669360 | 0.88 | CYP1A2 (0.65) | ALDH1A1THRBMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230278971-A1 | COMPOUNDS AFFECTING PIGMENT PRODUCTION AND METHODS FOR TREATMENT OF BACTERIAL DISEASES | VERSITECH LIMITED (HK) | 2023-09-07 | — | — | US | disclosed |
| US-20210309622-A1 | COMPOUNDS AFFECTING PIGMENT PRODUCTION AND METHODS FOR TREATMENT OF BACTERIAL DISEASES | VERSITECH LIMITED (HK) | 2021-10-07 | — | — | US | disclosed |
| US-11052078-B2 | Compounds affecting pigment production and methods for treatment of bacterial diseases | VERSITECH LIMITED (CN) | 2021-07-06 | — | — | US | disclosed |
| US-11040949-B2 | Compounds affecting pigment production and methods for treatment of bacterial diseases | VERSITECH LIMITED (CN) | 2021-06-22 | — | — | US | disclosed |
| US-20200392095-A1 | COMPOUNDS AFFECTING PIGMENT PRODUCTION AND METHODS FOR TREATMENT OF BACTERIAL DISEASES | THE UNIVERSITY OF HONG KONG (HK) | 2020-12-17 | — | — | US | disclosed |
| US-20200261438-A1 | COMPOUNDS AFFECTING PIGMENT PRODUCTION AND METHODS FOR TREATMENT OF BACTERIAL DISEASES | THE UNIVERSITY OF HONG KONG (HK) | 2020-08-20 | — | — | US | disclosed |
| US-20190022038-A1 | COMPOUNDS AFFECTING PIGMENT PRODUCTION AND METHODS FOR TREATMENT OF BACTERIAL DISEASES | VERSITECH LIMITED (HK) | 2019-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11040949-B2 | Compounds affecting pigment production and methods for treatment of bacterial diseases | TYR, ALAD, NQO1 | ALDH1A1 295/4885THRB 2978/4885MAPT 1574/4885 |
| US-20200392095-A1 | COMPOUNDS AFFECTING PIGMENT PRODUCTION AND METHODS FOR TREATMENT OF BACTERIAL DISEASES | TYR, ALAD, NQO1 | ALDH1A1 295/4885THRB 2978/4885MAPT 1574/4885 |
| US-11052078-B2 | Compounds affecting pigment production and methods for treatment of bacterial diseases | TYR, ALAD, NQO1 | ALDH1A1 295/4885THRB 2978/4885MAPT 1574/4885 |
| US-20210309622-A1 | COMPOUNDS AFFECTING PIGMENT PRODUCTION AND METHODS FOR TREATMENT OF BACTERIAL DISEASES | TYR, ALAD, NQO1 | ALDH1A1 295/4885THRB 2978/4885MAPT 1574/4885 |
| US-20200261438-A1 | COMPOUNDS AFFECTING PIGMENT PRODUCTION AND METHODS FOR TREATMENT OF BACTERIAL DISEASES | TYR, ALAD, NQO1 | ALDH1A1 295/4885THRB 2978/4885MAPT 1574/4885 |
| US-20230278971-A1 | COMPOUNDS AFFECTING PIGMENT PRODUCTION AND METHODS FOR TREATMENT OF BACTERIAL DISEASES | TYR, ALAD, NQO1 | ALDH1A1 295/4885THRB 2978/4885MAPT 1574/4885 |
| US-20190022038-A1 | COMPOUNDS AFFECTING PIGMENT PRODUCTION AND METHODS FOR TREATMENT OF BACTERIAL DISEASES | TYR, ALAD, NQO1 | ALDH1A1 295/4885THRB 2978/4885MAPT 1574/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.