SCHEMBL20657476

SCHEMBL20657476

CCCCCCCNc1ccc(NS(=O)(=O)c2ccc(C)cc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GHSR Q92847 3/20 0.55
▸ CA12 O43570 1/20 0.54
▸ CA1 P00915 1/20 0.54
▸ CA2 P00918 1/20 0.54
▸ CA9 Q16790 1/20 0.54
▸ ALDH1A1 P00352 7/20 0.54
▸ FFAR1 O14842 1/20 0.53
▸ FFAR4 Q5NUL3 1/20 0.53
▸ MAPT P10636 6/20 0.53
▸ MEN1 O00255 3/20 0.52
▸ KMT2A Q03164 3/20 0.52
▸ GAA P10253 3/20 0.52
▸ LMNA P02545 2/20 0.52
▸ ALOX12 P18054 2/20 0.52
▸ MAPK1 P28482 1/20 0.52
▸ GFER P55789 1/20 0.52
▸ MCL1 Q07820 1/20 0.52
▸ TDP1 Q9NUW8 1/20 0.52
▸ RECQL P46063 1/20 0.52
▸ SMN1; SMN2 Q16637 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8388394 0.87 GHSR (0.57) GHSRFFAR1FFAR4MAPTGAA
SCHEMBL8756421 0.87 GHSR (0.57) GHSRFFAR1FFAR4MAPTGAA
SCHEMBL8094483 0.83 FFAR1 (0.68) GHSRALDH1A1FFAR1FFAR4MAPT
SCHEMBL11508663 0.83 MAPT (0.64) MAPT
SCHEMBL11328551 0.83 MAPT (0.64) MAPT
SCHEMBL3682494 0.83 MAPT (0.64) MAPT
SCHEMBL11324887 0.83 MAPT (0.64) MAPT
SCHEMBL29183022 0.83 MAPT (0.64) MAPT
SCHEMBL11331977 0.83 MAPT (0.64) MAPT
SCHEMBL3678588 0.83 MAPT (0.64) MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200129458-A1 COMPOUND HAVING ENHANCING ACTIVITY FOR GLUCAGON-LIKE PEPTIDE-1 RECEPTOR ACTIONS AJINOMOTO CO., INC. (JP) 2020-04-30 — — US disclosed
US-20200129458-A1 COMPOUND HAVING ENHANCING ACTIVITY FOR GLUCAGON-LIKE PEPTIDE-1 RECEPTOR ACTIONS AJINOMOTO CO., INC. (JP) 2020-04-30 — — US disclosed
EP-3438091-A1 COMPOUND HAVING ENHANCING ACTIVITY FOR GLUCAGON-LIKE PEPTIDE-1 RECEPTOR ACTIONS AJINOMOTO CO., INC. (JP) 2019-02-06 — — EP disclosed
US-20190022039-A1 COMPOUND HAVING ENHANCING ACTIVITY FOR GLUCAGON-LIKE PEPTIDE-1 RECEPTOR ACTIONS AJINOMOTO CO., INC. (JP) 2019-01-24 — — US disclosed
US-20190022039-A1 COMPOUND HAVING ENHANCING ACTIVITY FOR GLUCAGON-LIKE PEPTIDE-1 RECEPTOR ACTIONS AJINOMOTO CO., INC. (JP) 2019-01-24 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200129458-A1 COMPOUND HAVING ENHANCING ACTIVITY FOR GLUCAGON-LIKE PEPTIDE-1 RECEPTOR ACTIONS GLP1R, GPR119, GIPR GHSR 6/4885CA12 4329/4885CA1 3303/4885
US-20190022039-A1 COMPOUND HAVING ENHANCING ACTIVITY FOR GLUCAGON-LIKE PEPTIDE-1 RECEPTOR ACTIONS GLP1R, GPR119, GIPR GHSR 6/4885CA12 4329/4885CA1 3303/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback