SCHEMBL2065835

SCHEMBL2065835

CCc1ccsc1C=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6816923 0.85 PRKCI (0.33)
SCHEMBL12339005 0.84 NPC1 (0.35)
SCHEMBL6819727 0.82 TYR (0.38)
SCHEMBL18825997 0.81 HIF1A (0.40)
SCHEMBL28372682 0.80
SCHEMBL255742 0.80
SCHEMBL9632650 0.80
SCHEMBL3716800 0.80
SCHEMBL1491977 0.80
SCHEMBL9632119 0.79 SLC6A1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250327191-A1 CORROSSION INHIBITOR COMPOSITIONS TATA CONSULTANCY SERVICES LIMITED (IN) 2025-10-23 US claimed
EP-4636130-A1 CORROSSION INHIBITOR COMPOSITIONS Tata Consultancy Services Limited (IN) 2025-10-22 EP claimed
US-20250327191-A1 CORROSSION INHIBITOR COMPOSITIONS TATA CONSULTANCY SERVICES LIMITED (IN) 2025-10-23 US disclosed
EP-4636130-A1 CORROSSION INHIBITOR COMPOSITIONS Tata Consultancy Services Limited (IN) 2025-10-22 EP disclosed
US-11718607-B2 Atypical coupling method for the preparation of 1,2-di(thiophen-2-yl)ethene-1,2-diol compounds via a Cu(II) catalyst QATAR UNIVERSITY (QA) 2023-08-08 US disclosed
US-20220289727-A1 ENZYME INHIBITORS KALVISTA PHARMACEUTICALS LIMITED (GB) 2022-09-15 US disclosed
US-20220204487-A1 ATYPICAL COUPLING METHOD FOR THE PREPARATION OF 1,2-DI(THIOPHEN-2-YL)ETHENE-1,2-DIOL COMPOUNDS VIA A CU(II) CATALYST QATAR UNIVERSITY (QA) 2022-06-30 US disclosed
EP-4017850-A1 ENZYME INHIBITORS Kalvista Pharmaceuticals Limited (GB) 2022-06-29 EP disclosed
CN-114258392-A Enzyme inhibitors 卡尔维斯塔制药有限公司 2022-03-29 CN disclosed
CN-108473911-B Formylthiophenes and their use in flavour and fragrance compositions 国际香料和香精公司 2021-10-29 CN disclosed
WO-2021032935-A1 ENZYME INHIBITORS KALVISTA PHARMACEUTICALS LIMITED (GB) 2021-02-25 WO disclosed
US-5656642-A Peripheral vasodilating agent containing piperidine derivative as active ingredient OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1997-08-12 US disclosed
WO-1997011705-A1 PHOSPHORYLAMIDES, THEIR PREPARATION AND USE TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1997-04-03 WO disclosed
CN-1104412-A Peripheral Vasodilating agent containing N-acylated 4-amino piperidine derivatives as active ingredients OTSUKA PHARMA CO LTD (JP) 1995-06-28 CN disclosed
EP-0650476-A1 PERIPHERAL VASODILATING AGENT CONTAINING N-ACYLATED 4-AMINO PIPERIDINE DERIVATIVES AS ACTIVE INGREDIENTS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1995-05-03 EP disclosed
WO-1994022826-A1 PERIPHERAL VASODILATING AGENT CONTAINING N-ACYLATED 4-AMINO PIPERIDINE DERIVATIVES AS ACTIVE INGREDIENTS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1994-10-13 WO disclosed
US-5126461-A Silica in organic solution SHELL RESEARCH LIMITED (GB) 1992-06-30 US disclosed
US-5120861-A DIAZIRINE DERIVATIVES OF AROMATIC HETEROCYCLIC COMPOUNDS SHELL RESEARCH LIMITED (GB) 1992-06-09 US disclosed
EP-0432817-A1 Diazirine derivatives of aromatic heterocyclic compounds SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1991-06-19 EP disclosed
EP-0432818-A2 Process for opening cyclopropane rings SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1991-06-19 EP disclosed