SCHEMBL2065987

SCHEMBL2065987

CCCc1ccc2nc(C(F)(F)F)cn2n1

nearest known ligand 0.58

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PDE10A Q9Y233 8/20 0.58
MCHR1 Q99705 1/20 0.36
AHR P35869 1/20 0.34
SCN5A Q14524 1/20 0.34
MAPT P10636 1/20 0.33
GABRA2 P47869 1/20 0.33
GABRB2 P47870 1/20 0.33
DPP4 P27487 1/20 0.32
DPP8 Q6V1X1 1/20 0.32
DPP9 Q86TI2 1/20 0.32
DPP7 Q9UHL4 1/20 0.32
CTSK P43235 3/20 0.32
CTSS P25774 2/20 0.32
KDM4E B2RXH2 1/20 0.31
PDCD1 Q15116 1/20 0.31
CD274 Q9NZQ7 1/20 0.31
CYP19A1 P11511 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6468498 0.88 PDE10A (0.54) PDE10AAHRSCN5ADPP4DPP8
SCHEMBL2066636 0.80 PDE10A (0.40) PDE10AMCHR1KDM4EPDCD1CD274
SCHEMBL2066059 0.80 PDE10A (0.54) PDE10AAHRGABRA2GABRB2PDCD1
SCHEMBL2066941 0.80 PDE10A (0.38) PDE10AMCHR1AHRKDM4EPDCD1
SCHEMBL2067442 0.78 PDE10A (0.39) PDE10AMCHR1KDM4EPDCD1CD274
SCHEMBL2068243 0.78 PDE10A (0.53) PDE10AAHRMAPTKDM4EPDCD1
SCHEMBL2066211 0.76 PDE10A (0.38) PDE10AAHRKDM4EPDCD1CD274
SCHEMBL12962511 0.76 PDE10A (0.45) PDE10AAHRSCN5ADPP4DPP8
SCHEMBL16984641 0.74 PDE10A (1.00) PDE10A
SCHEMBL2066057 0.74 PDE10A (0.36) PDE10AKDM4EPDCD1CD274

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8148524-B2 Process for producing sulfonyl chloride compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-04-03 US disclosed
EP-1932846-B1 METHOD FOR PRODUCING SULFONYL CHLORIDE COMPOUND SUMITOMO CHEMICAL CO (JP) 2010-10-27 EP disclosed
US-20090247748-A1 PROCESS FOR PRODUCING SULFONYL CHLORIDE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-10-01 US disclosed
EP-1932846-A1 METHOD FOR PRODUCING SULFONYL CHLORIDE COMPOUND Sumitomo Chemical Company, Limited (JP) 2008-06-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090247748-A1 PROCESS FOR PRODUCING SULFONYL CHLORIDE COMPOUND SALL4, CLCN2, CLIC1 PDE10A 3486/4885MCHR1 2788/4885AHR 1818/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.