SCHEMBL2066211

SCHEMBL2066211

CCCc1ccc2nc(Br)cn2n1

nearest known ligand 0.38

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PDE10A Q9Y233 3/20 0.38
AHR P35869 10/20 0.36
KDM4E B2RXH2 2/20 0.35
NPC1 O15118 2/20 0.35
TP53 P04637 2/20 0.35
RAB9A P51151 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
LMNA P02545 1/20 0.35
PDCD1 Q15116 1/20 0.33
CD274 Q9NZQ7 1/20 0.33
PSD A5PKW4 1/20 0.32
ALDH1A1 P00352 1/20 0.31
HPGD P15428 1/20 0.31
HSD17B10 Q99714 1/20 0.31
CYP19A1 P11511 1/20 0.30
DYRK1A Q13627 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2065680 0.90 PDE10A (0.36) PDE10AAHRTP53SMN1; SMN2
SCHEMBL2067911 0.86 AHR (0.38) PDE10AAHRKDM4ENPC1RAB9A
SCHEMBL2066636 0.84 PDE10A (0.40) PDE10AKDM4ENPC1TP53RAB9A
SCHEMBL2067442 0.81 PDE10A (0.39) PDE10AKDM4ENPC1TP53RAB9A
SCHEMBL2068243 0.81 PDE10A (0.53) PDE10AAHRKDM4ETP53SMN1; SMN2
SCHEMBL2066057 0.81 PDE10A (0.36) PDE10AKDM4ENPC1RAB9APDCD1
SCHEMBL2066059 0.80 PDE10A (0.54) PDE10AAHRNPC1RAB9APDCD1
SCHEMBL2066941 0.80 PDE10A (0.38) PDE10AAHRKDM4EPDCD1CD274
SCHEMBL2066534 0.79 AHR (0.35) PDE10AAHRTP53PDCD1CD274
SCHEMBL2066236 0.76 PDE10A (0.38) PDE10AAHRKDM4EHSD17B10CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8148524-B2 Process for producing sulfonyl chloride compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-04-03 US disclosed
EP-1932846-B1 METHOD FOR PRODUCING SULFONYL CHLORIDE COMPOUND SUMITOMO CHEMICAL CO (JP) 2010-10-27 EP disclosed
US-20090247748-A1 PROCESS FOR PRODUCING SULFONYL CHLORIDE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-10-01 US disclosed
EP-1932846-A1 METHOD FOR PRODUCING SULFONYL CHLORIDE COMPOUND Sumitomo Chemical Company, Limited (JP) 2008-06-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090247748-A1 PROCESS FOR PRODUCING SULFONYL CHLORIDE COMPOUND SALL4, CLCN2, CLIC1 PDE10A 3486/4885AHR 1818/4885KDM4E 3606/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.