Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GART | P22102 | 13/20 | 0.62 |
| ▸ | FOLR1 | P15328 | 11/20 | 0.56 |
| ▸ | SLC46A1 | Q96NT5 | 8/20 | 0.56 |
| ▸ | SLC19A1 | P41440 | 5/20 | 0.56 |
| ▸ | FOLR2 | P14207 | 4/20 | 0.56 |
| ▸ | ATIC | P31939 | 5/20 | 0.55 |
| ▸ | SHMT1 | P34896 | 3/20 | 0.52 |
| ▸ | SHMT2 | P34897 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6829597 | 1.00 | GART (0.62) | GARTFOLR1SLC46A1SLC19A1FOLR2 | |
| SCHEMBL1065440 | 1.00 | GART (0.62) | GARTFOLR1SLC46A1SLC19A1FOLR2 | |
| SCHEMBL1065450 | 1.00 | GART (0.62) | GARTFOLR1SLC46A1SLC19A1FOLR2 | |
| SCHEMBL27529613 | 1.00 | GART (0.62) | GARTFOLR1SLC46A1SLC19A1FOLR2 | |
| SCHEMBL7745908 | 0.88 | GART (0.75) | GARTFOLR1SLC46A1SLC19A1FOLR2 | |
| Lometrexol SCHEMBL18530 | 0.85 | GART (0.78) | GARTFOLR1SLC46A1SLC19A1FOLR2 | |
| Lometrexol SCHEMBL21248426 | 0.85 | GART (0.77) | GARTFOLR1SLC46A1SLC19A1FOLR2 | |
| SCHEMBL9380609 | 0.82 | DHFR (0.59) | GARTFOLR1SLC46A1SLC19A1FOLR2 | |
| SCHEMBL9381796 | 0.82 | DHFR (0.59) | GARTFOLR1SLC46A1SLC19A1FOLR2 | |
| SCHEMBL14403392 | 0.82 | DHFR (0.59) | GARTFOLR1SLC46A1SLC19A1FOLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250354166-A1 | LENTIVIRAL VECTORS USEFUL FOR THE TREATMENT OF DISEASE | CSL BEHRING L L C (US) | 2025-11-20 | — | — | US | disclosed |
| EP-4190339-B1 | A MODULATABLE SWITCH FOR SELECTION OF DONOR MODIFIED CELLS | CSL BEHRING GENE THERAPY INC (US) | 2025-07-02 | — | — | EP | disclosed |
| EP-4329822-A1 | LENTIVIRAL VECTORS USEFUL FOR THE TREATMENT OF DISEASE | CSL Behring L.L.C. (US) | 2024-03-06 | — | — | EP | disclosed |
| US-20230355674-A1 | DONOR T-CELLS WITH KILL SWITCH | CSL BEHRING LLC (US) | 2023-11-09 | — | — | US | disclosed |
| EP-4190339-A1 | A MODULATABLE SWITCH FOR SELECTION OF DONOR MODIFIED CELLS | CSL Behring Gene Therapy, Inc. (US) | 2023-06-07 | — | — | EP | disclosed |
| EP-4172335-A1 | DONOR T-CELLS WITH KILL SWITCH | CSL Behring LLC (US) | 2023-05-03 | — | — | EP | disclosed |
| EP-3654994-B1 | A MODULATABLE SWITCH FOR SELECTION OF DONOR MODIFIED CELLS | CSL BEHRING GENE THERAPY INC (US) | 2022-12-28 | — | — | EP | disclosed |
| US-20220072046-A1 | MODULATABLE SWITCH FOR SELECTION OF DONOR MODIFIED CELLS | CSL BEHRING GENE THERAPY INC (US) | 2022-03-10 | — | — | US | disclosed |
| US-11213548-B2 | Modulatable switch for selection of donor modified cells | CSL BEHRING GENE THERAPY, INC. (US) | 2022-01-04 | — | — | US | disclosed |
| WO-2021263070-A1 | DONOR T-CELLS WITH KILL SWITCH | CSL BEHRING LLC (US) | 2021-12-30 | — | — | WO | disclosed |
| US-20210340563-A1 | DONOR T-CELLS WITH KILL SWITCH | CSL BEHRING LLC (US) | 2021-11-04 | — | — | US | disclosed |
| EP-3897745-A1 | HAEMATOPOIETIC STEM CELL-GENE THERAPY FOR WISKOTT-ALDRICH SYNDROME | CSL Behring LLC (US) | 2021-10-27 | — | — | EP | disclosed |
| US-20210316013-A1 | HAEMATOPOIETIC STEM CELL-GENE THERAPY FOR WISKOTT-ALDRICH SYNDROME | CSL BEHRING LLC (US) | 2021-10-14 | — | — | US | disclosed |
| WO-2020139796-A1 | HAEMATOPOIETIC STEM CELL-GENE THERAPY FOR WISKOTT-ALDRICH SYNDROME | CSL BEHRING L.L.C. (US) | 2020-07-02 | — | — | WO | disclosed |
| EP-3654994-A1 | A MODULATABLE SWITCH FOR SELECTION OF DONOR MODIFIED CELLS | Calimmune, Inc. (US) | 2020-05-27 | — | — | EP | disclosed |
| US-20200038444-A1 | MODULATABLE SWITCH FOR SELECTION OF DONOR MODIFIED CELLS | CALIMMUNE INC (US) | 2020-02-06 | — | — | US | disclosed |
| US-10426798-B2 | Modulatable switch for selection of donor modified cells | Calimmune, Inc. (US) | 2019-10-01 | — | — | US | disclosed |
| US-20190054119-A1 | MODULATABLE SWITCH FOR SELECTION OF DONOR MODIFIED CELLS | CALIMMUNE INC (US) | 2019-02-21 | — | — | US | disclosed |
| WO-2019018491-A1 | A MODULATABLE SWITCH FOR SELECTION OF DONOR MODIFIED CELLS | Calimmune, Inc. (US) | 2019-01-24 | — | — | WO | disclosed |