Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL10926100 | 0.81 | SIGMAR1 (0.47) | HRH3SIGMAR1 | |
| SCHEMBL3219828 | 0.75 | SIGMAR1 (0.47) | HRH3SIGMAR1MAOAMAOBHTR1A | |
| SCHEMBL12023880 | 0.73 | SIGMAR1 (0.75) | HRH3SIGMAR1HTR1ASLC6A4 | |
| SCHEMBL29356024 | 0.72 | HRH3 (1.00) | HRH3SIGMAR1MAOAMAOBSLC6A4 | |
| SCHEMBL10499190 | 0.72 | SIGMAR1 (0.73) | HRH3SIGMAR1MAOAMAOBHTR1A | |
| SCHEMBL2066095 | 0.72 | BCHE (0.44) | HRH3SIGMAR1 | |
| SCHEMBL11156977 | 0.71 | HRH3 (0.96) | HRH3SIGMAR1MAOAMAOBSLC6A4 | |
| SCHEMBL9881343 | 0.70 | SIGMAR1 (0.65) | HRH3SIGMAR1MAOAMAOBHTR1A | |
| SCHEMBL3590302 | 0.70 | SIGMAR1 (0.69) | HRH3SIGMAR1HTR1ASLC6A4 | |
| SCHEMBL6795798 | 0.70 | SIGMAR1 (0.64) | HRH3SIGMAR1MAOAMAOBHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2628728-B1 | PROCESS FOR THE OPTICAL RESOLUTION OF 1-(4-METHOXYBENZYL)-OCTAHYDROISOQUINOLINE | DIVI'S LABORATORIES LTD (IN) | 2017-04-19 | — | — | EP | disclosed |
| CN-103319406-A | Resolution of 1-(4-methoxybenzyl)-octahydro-isoquinoline | DIVIS LAB LTD | 2013-09-25 | — | — | CN | disclosed |
| EP-2628728-A1 | Process for the optical resolution of 1-(4-methoxybenzyl)-octahydro-isoquinoline | Divi's Laboratories Limited (IN) | 2013-08-21 | — | — | EP | disclosed |
| US-8148527-B1 | Resolution of 1-(4-methoxybenzyl)-octahydro-isoquinoline | Divi's Laboratories, Ltd. (IN) | 2012-04-03 | — | — | US | disclosed |