Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 6/20 | 0.65 |
| ▸ | MAOB | P27338 | 6/20 | 0.65 |
| ▸ | KDM1A | O60341 | 3/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | FUCA1 | P04066 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15456202 | 0.81 | MAOA (0.62) | MAOAMAOBKDM1ASMN1; SMN2CHRM2 | |
| SCHEMBL13276465 | 0.81 | MAOA (0.62) | MAOAMAOBKDM1ASMN1; SMN2CHRM2 | |
| SCHEMBL18920810 | 0.81 | MAOA (0.62) | MAOAMAOBKDM1ASMN1; SMN2CHRM2 | |
| SCHEMBL13276199 | 0.81 | MAOA (0.62) | MAOAMAOBKDM1ASMN1; SMN2CHRM2 | |
| SCHEMBL15456460 | 0.81 | MAOA (0.62) | MAOAMAOBKDM1ASMN1; SMN2CHRM2 | |
| SCHEMBL5539196 | 0.80 | MAOA (0.61) | MAOAMAOBKDM1ASMN1; SMN2CHRM2 | |
| SCHEMBL29785655 | 0.80 | MAOA (0.61) | MAOAMAOBKDM1ASMN1; SMN2CHRM2 | |
| SCHEMBL1732541 | 0.80 | MAOA (0.61) | MAOAMAOBKDM1ASMN1; SMN2CHRM2 | |
| SCHEMBL13263154 | 0.79 | KDM1A (1.00) | MAOAMAOBKDM1A | |
| SCHEMBL237945 | 0.79 | KDM1A (1.00) | MAOAMAOBKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2791137-B1 | PYRAZOLOPYRIDINE DERIVATIVES, PREPARATION PROCESS THEREFOR AND THERAPEUTIC USE THEREOF | SANOFI SA (FR) | 2019-01-23 | — | — | EP | disclosed |