Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | KIT | P10721 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.53 |
| ▸ | RELA | Q04206 | 1/20 | 0.53 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.51 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.51 |
| ▸ | MAOB | P27338 | 3/20 | 0.51 |
| ▸ | GABRP | O00591 | 3/20 | 0.51 |
| ▸ | GABRD | O14764 | 3/20 | 0.51 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.51 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.51 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15268294 | 0.86 | FLT3 (0.65) | FLT3KMT2AMAPTMEN1NPC1 | |
| SCHEMBL16521507 | 0.85 | MAPT (0.71) | FLT3KMT2AMAPTMEN1NPC1 | |
| SCHEMBL16521509 | 0.84 | AR (0.63) | FLT3KMT2AMAPTMEN1NPC1 | |
| SCHEMBL16521506 | 0.82 | ADORA3 (0.69) | FLT3KMT2AMAPTMEN1NPC1 | |
| SCHEMBL16525547 | 0.81 | POLB (0.73) | FLT3KMT2AMAPTMEN1NPC1 | |
| SCHEMBL13287220 | 0.79 | ABCB1 (0.74) | FLT3KMT2AMAPTMEN1NPC1 | |
| SCHEMBL15277727 | 0.77 | FLT3 (0.56) | FLT3KMT2AMAPTMEN1NPC1 | |
| SCHEMBL16521508 | 0.77 | ABCB1 (0.55) | FLT3KMT2AMAPTMEN1NPC1 | |
| SCHEMBL28942867 | 0.77 | CDK8 (0.73) | FLT3KMT2AMAPTMEN1NPC1 | |
| SCHEMBL15268315 | 0.77 | MAOB (0.68) | FLT3KMT2AMAPTMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2828248-B1 | FLAVONE DERIVATIVES AND THEIR USE | TWINCORE GMBH (DE) | 2019-01-23 | — | — | EP | disclosed |