Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.53 |
| ▸ | MET | P08581 | 1/20 | 0.48 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.45 |
| ▸ | CDK4 | P11802 | 2/20 | 0.45 |
| ▸ | CCND1 | P24385 | 2/20 | 0.45 |
| ▸ | SLC9A1 | P19634 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL562206 | 0.98 | P2RX7 (0.54) | P2RX7METTLR8CDK4CCND1 | |
| SCHEMBL4870962 | 0.81 | P2RX7 (0.52) | P2RX7METCDK4CCND1LMNA | |
| SCHEMBL12640059 | 0.80 | RPS6KA5 (0.52) | P2RX7METRPS6KA5 | |
| SCHEMBL10824919 | 0.79 | HTT (0.54) | TLR8CDK4CCND1LMNASMN1; SMN2 | |
| SCHEMBL3868979 | 0.78 | TDP1 (0.68) | P2RX7SLC9A1LMNASMN1; SMN2HTT | |
| SCHEMBL6321085 | 0.78 | TDP1 (0.68) | P2RX7SLC9A1LMNASMN1; SMN2HTT | |
| SCHEMBL9853336 | 0.78 | TDP1 (0.68) | P2RX7SLC9A1LMNASMN1; SMN2HTT | |
| SCHEMBL9038701 | 0.78 | TDP1 (0.68) | P2RX7SLC9A1LMNASMN1; SMN2HTT | |
| SCHEMBL9038339 | 0.78 | TDP1 (0.68) | P2RX7SLC9A1LMNASMN1; SMN2HTT | |
| SCHEMBL4888041 | 0.78 | TDP1 (0.68) | P2RX7SLC9A1LMNASMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10375962-B2 | Heterocycle derivatives as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-08-13 | — | — | US | disclosed |
| US-20190021329-A1 | HETEROCYCLE DERIVATIVES AS PESTICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10375962-B2 | Heterocycle derivatives as pesticides | DDT, ACHE, CBR1 | P2RX7 669/4885MET 3939/4885TLR8 4821/4885 |
| US-20190021329-A1 | HETEROCYCLE DERIVATIVES AS PESTICIDES | DDT, ACHE, CBR1 | P2RX7 669/4885MET 3939/4885TLR8 4821/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.