SCHEMBL2066751

SCHEMBL2066751

CCCCc1ccc2nc(F)c(S(N)(=O)=O)n2n1

nearest known ligand 0.36

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CA2 P00918 6/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
TLR7 Q9NYK1 3/20 0.36
CA1 P00915 4/20 0.33
CA9 Q16790 4/20 0.33
CA12 O43570 3/20 0.33
PDPK1 O15530 2/20 0.32
ALOX5 P09917 1/20 0.31
PDE10A Q9Y233 1/20 0.30
CCNT1 O60563 1/20 0.30
CDK7 P50613 1/20 0.30
CDK9 P50750 1/20 0.30
CCNH P51946 1/20 0.30
NOS2 P35228 1/20 0.30
TSHR P16473 1/20 0.30
CA7 P43166 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2066698 0.92 CA2 (0.33) CA2PDE10A
SCHEMBL2066766 0.87 TLR7 (0.33) TLR7ALOX5PDE10A
SCHEMBL2065783 0.87 AKT1 (0.34) CA2CA1CA9CA12
SCHEMBL2066570 0.85 CA2 (0.36) CA2SMN1; SMN2TLR7CA1CA9
SCHEMBL2066200 0.85 CA2 (0.36) CA2SMN1; SMN2TLR7CA1CA9
SCHEMBL2846443 0.81 PDE10A (0.32) PDE10A
SCHEMBL2066208 0.81 TLR7 (0.34) TLR7
SCHEMBL3342381 0.80 PDE10A (0.32) PDE10A
SCHEMBL3342925 0.79 PDE10A (0.31) PDE10A
SCHEMBL2065623 0.79 PDE10A (0.31) PDE10A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8148524-B2 Process for producing sulfonyl chloride compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-04-03 US disclosed
EP-1932846-B1 METHOD FOR PRODUCING SULFONYL CHLORIDE COMPOUND SUMITOMO CHEMICAL CO (JP) 2010-10-27 EP disclosed
US-20090247748-A1 PROCESS FOR PRODUCING SULFONYL CHLORIDE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-10-01 US disclosed
EP-1932846-A1 METHOD FOR PRODUCING SULFONYL CHLORIDE COMPOUND Sumitomo Chemical Company, Limited (JP) 2008-06-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090247748-A1 PROCESS FOR PRODUCING SULFONYL CHLORIDE COMPOUND SALL4, CLCN2, CLIC1 CA2 176/4885SMN1; SMN2 3594/4885TLR7 3228/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.