Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 6/20 | 0.61 |
| ▸ | TLR2 | O60603 | 1/20 | 0.58 |
| ▸ | KISS1R | Q969F8 | 2/20 | 0.55 |
| ▸ | MMP3 | P08254 | 2/20 | 0.54 |
| ▸ | MMP9 | P14780 | 1/20 | 0.54 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.53 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.53 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.53 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.53 |
| ▸ | NPY4R | P50391 | 3/20 | 0.53 |
| ▸ | NPY1R | P25929 | 2/20 | 0.53 |
| ▸ | NPY2R | P49146 | 2/20 | 0.53 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.53 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.53 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.53 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.52 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.52 |
| ▸ | REN | P00797 | 1/20 | 0.51 |
| ▸ | F2 | P00734 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22030266 | 0.94 | OPRK1 (0.63) | OPRK1KISS1RMMP3MMP9NPY4R | |
| SCHEMBL18413059 | 0.93 | OPRK1 (0.61) | OPRK1TLR2KISS1RNPY4RNPY1R | |
| SCHEMBL12317346 | 0.93 | OPRK1 (0.61) | OPRK1TLR2KISS1RNPY4RNPY1R | |
| SCHEMBL20363344 | 0.93 | OPRK1 (0.61) | OPRK1TLR2KISS1RNPY4RNPY1R | |
| SCHEMBL22957091 | 0.93 | OPRK1 (0.61) | OPRK1TLR2KISS1RNPY4RNPY1R | |
| SCHEMBL23734113 | 0.92 | KISS1R (0.61) | OPRK1KISS1RNPY4RNPY1RNPY2R | |
| SCHEMBL11927477 | 0.92 | OPRK1 (0.60) | OPRK1KISS1RNPY4RNPY1RNPY2R | |
| SCHEMBL11927456 | 0.92 | OPRK1 (0.60) | OPRK1KISS1RNPY4RNPY1RNPY2R | |
| SCHEMBL11931479 | 0.92 | OPRK1 (0.60) | OPRK1KISS1RNPY4RNPY1RNPY2R | |
| SCHEMBL11927461 | 0.92 | OPRK1 (0.60) | OPRK1KISS1RNPY4RNPY1RNPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019015644-A1 | PEPTIDE AMIDE COMPOUND AND PREPARATION METHOD AND MEDICAL USE THEREOF | 四川海思科制药有限公司 | 2019-01-24 | — | — | WO | disclosed |