SCHEMBL2066939

SCHEMBL2066939

CCCCc1ccc2nc(Br)c(S(=O)(=O)Cl)n2n1

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 3/20 0.33
JAK1 P23458 1/20 0.31
JAK3 P52333 1/20 0.31
ALOX5 P09917 1/20 0.31
CCNT1 O60563 1/20 0.30
CDK7 P50613 1/20 0.30
CDK9 P50750 1/20 0.30
CCNH P51946 1/20 0.30
NOS2 P35228 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2065990 0.92 JAK1 (0.32) JAK1JAK3
SCHEMBL2066570 0.87 CA2 (0.36) TLR7ALOX5CCNT1CDK7CDK9
SCHEMBL2066410 0.87 JAK1 (0.33) JAK1JAK3
SCHEMBL2065543 0.86 PDE10A (0.36) TLR7ALOX5
SCHEMBL2066766 0.85 TLR7 (0.33) TLR7ALOX5
SCHEMBL2066347 0.81 TLR7 (0.32) TLR7JAK1JAK3
SCHEMBL2066797 0.79 CA2 (0.33) CDK7CDK9
SCHEMBL2066260 0.77 PDE10A (0.38)
SCHEMBL2066696 0.77 PDE10A (0.37)
SCHEMBL2066602 0.77 PDE10A (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8148524-B2 Process for producing sulfonyl chloride compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-04-03 US disclosed
EP-1932846-B1 METHOD FOR PRODUCING SULFONYL CHLORIDE COMPOUND SUMITOMO CHEMICAL CO (JP) 2010-10-27 EP disclosed
US-20090247748-A1 PROCESS FOR PRODUCING SULFONYL CHLORIDE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-10-01 US disclosed
EP-1932846-A1 METHOD FOR PRODUCING SULFONYL CHLORIDE COMPOUND Sumitomo Chemical Company, Limited (JP) 2008-06-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090247748-A1 PROCESS FOR PRODUCING SULFONYL CHLORIDE COMPOUND SALL4, CLCN2, CLIC1 TLR7 3228/4885JAK1 679/4885JAK3 1687/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.