Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 2/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.48 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15415970 | 0.86 | CASP3 (0.54) | CASP3CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL7917885 | 0.84 | LMNA (0.53) | CASP3CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL22667121 | 0.84 | CHRM5 (0.47) | CASP3CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL1752279 | 0.83 | CHRM5 (0.62) | CASP3CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL29992308 | 0.81 | CASP3 (0.49) | CASP3CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL26342105 | 0.79 | CHRM5 (0.47) | CASP3CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL2274453 | 0.79 | CASP3 (0.47) | CASP3CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL18740324 | 0.78 | KMT2A (0.47) | CASP3CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL15420762 | 0.78 | MEN1 (0.61) | CASP3CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL20300563 | 0.77 | MEN1 (0.57) | CASP3CHRM2CHRM4CHRM5CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210163409-A1 | ALTERNATE PROCESSES FOR THE PREPARATION OF PYRROLIDINE DERIVATIVES | Dr Reddys Laboratories Ltd (IN) | 2021-06-03 | — | — | US | disclosed |
| US-20210163409-A1 | ALTERNATE PROCESSES FOR THE PREPARATION OF PYRROLIDINE DERIVATIVES | Dr Reddys Laboratories Ltd (IN) | 2021-06-03 | — | — | US | disclosed |
| WO-2019016745-A1 | ALTERNATE PROCESSES FOR THE PREPARATION OF PYRROLIDINE DERIVATIVES | DR. REDDY'S LABORATORIES LIMITED (IN) | 2019-01-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210163409-A1 | ALTERNATE PROCESSES FOR THE PREPARATION OF PYRROLIDINE DERIVATIVES | PRKD1, JAK1, JAK3 | CASP3 1916/4885CHRM2 4786/4885CHRM4 4491/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.