Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | SMO | Q99835 | 5/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.39 |
| ▸ | KIT | P10721 | 4/20 | 0.38 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ERG | P11308 | 1/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20116688 | 0.83 | CNR1 (0.39) | CNR1CNR2SMODGAT1KIT | |
| SCHEMBL20116798 | 0.82 | KIT (0.42) | SMOKITSMN1; SMN2HTTLMNA | |
| SCHEMBL20116682 | 0.81 | NPC1 (0.53) | DGAT1KITSMN1; SMN2HTTLMNA | |
| SCHEMBL20116847 | 0.80 | NPC1 (0.42) | SMOKITSMN1; SMN2HTTLMNA | |
| SCHEMBL20116791 | 0.79 | SMO (0.43) | SMODGAT1SMN1; SMN2HTTLMNA | |
| SCHEMBL20116766 | 0.78 | NPC1 (0.42) | KITSMN1; SMN2HTTNR1H4GAA | |
| SCHEMBL20676516 | 0.78 | SMN1; SMN2 (0.38) | CNR1CNR2SMODGAT1KIT | |
| SCHEMBL20676636 | 0.77 | LMNA (0.46) | SMN1; SMN2HTTLMNAMAPTNPSR1 | |
| SCHEMBL20116662 | 0.77 | GRM5 (0.44) | SMN1; SMN2HTTLMNAMAPTNPSR1 | |
| SCHEMBL20116753 | 0.76 | GRM5 (0.54) | SMOKITSMN1; SMN2HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019209948-A9 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-01-02 | — | — | WO | disclosed |
| WO-2019018795-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS (US) | 2019-01-24 | — | — | WO | disclosed |