Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB1 | P15086 | 1/20 | 0.56 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.56 |
| ▸ | ECE1 | P42892 | 2/20 | 0.54 |
| ▸ | ACE | P12821 | 1/20 | 0.53 |
| ▸ | MME | P08473 | 1/20 | 0.53 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.52 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.52 |
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 0.52 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.51 |
| ▸ | CTSL | P07711 | 2/20 | 0.51 |
| ▸ | TLR2 | O60603 | 2/20 | 0.51 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.49 |
| ▸ | CTSS | P25774 | 1/20 | 0.48 |
| ▸ | MMP3 | P08254 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31235811 | 0.90 | CPB1 (0.59) | CPB1CPB2ECE1ACEMME | |
| SCHEMBL29387284 | 0.88 | CPB1 (0.55) | CPB1CPB2ECE1ACESIRT2 | |
| SCHEMBL29576990 | 0.88 | ECE1 (0.63) | CPB1CPB2ECE1ACEMME | |
| SCHEMBL20263591 | 0.88 | MME (0.59) | ECE1MMEPSMB1 | |
| SCHEMBL20677213 | 0.88 | MME (0.59) | ECE1MMEPSMB1 | |
| SCHEMBL24992811 | 0.88 | MME (0.59) | ECE1MMEPSMB1 | |
| SCHEMBL19384748 | 0.88 | MME (0.59) | ECE1MMEPSMB1 | |
| SCHEMBL14371944 | 0.88 | MME (0.59) | ECE1MMEPSMB1 | |
| SCHEMBL28819863 | 0.87 | MME (0.60) | ECE1MMEPSMB1 | |
| SCHEMBL28645693 | 0.87 | MME (0.60) | ECE1MMEPSMB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3432934-A1 | PRODRUGS OF CYTOTOXIC ACTIVE AGENTS HAVING ENZYMATICALLY CLEAVABLE GROUPS | Bayer Pharma Aktiengesellschaft (DE) | 2019-01-30 | — | — | EP | disclosed |