Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 5/20 | 0.35 |
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | CA9 | Q16790 | 3/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA4 | P22748 | 2/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | WRN | Q14191 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13541914 | 0.88 | LMNA (0.47) | MGLLLMNAPKMGSK3AGSK3B | |
| SCHEMBL17841834 | 0.86 | MGLL (0.42) | MGLLLMNAPKMGSK3AGSK3B | |
| SCHEMBL24797605 | 0.86 | MGLL (0.42) | MGLLLMNAPKMGSK3AGSK3B | |
| SCHEMBL24798072 | 0.86 | MGLL (0.42) | MGLLLMNAPKMGSK3AGSK3B | |
| SCHEMBL17841923 | 0.86 | MGLL (0.42) | MGLLLMNAPKMGSK3AGSK3B | |
| SCHEMBL24797571 | 0.84 | MGLL (0.43) | MGLLLMNAPKMGSK3AGSK3B | |
| SCHEMBL24255821 | 0.84 | MGLL (0.43) | MGLLLMNAPKMGSK3AGSK3B | |
| SCHEMBL22311942 | 0.84 | MGLL (0.43) | MGLLLMNAPKMGSK3AGSK3B | |
| SCHEMBL29398497 | 0.84 | LMNA (0.42) | MGLLLMNAPKMGSK3AGSK3B | |
| SCHEMBL24797572 | 0.84 | MGLL (0.43) | MGLLLMNAPKMGSK3AGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3432934-A1 | PRODRUGS OF CYTOTOXIC ACTIVE AGENTS HAVING ENZYMATICALLY CLEAVABLE GROUPS | Bayer Pharma Aktiengesellschaft (DE) | 2019-01-30 | — | — | EP | disclosed |