Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Cellobiose. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 6/20 | 0.49 |
| ▸ | CA1 | P00915 | 6/20 | 0.49 |
| ▸ | CA2 | P00918 | 6/20 | 0.49 |
| ▸ | CA9 | Q16790 | 6/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.49 |
| ▸ | AMY2A | P04746 | 2/20 | 0.49 |
| ▸ | TYR | P14679 | 2/20 | 0.48 |
| ▸ | FGF1 | P05230 | 1/20 | 0.48 |
| ▸ | FGF2 | P09038 | 1/20 | 0.48 |
| ▸ | VEGFA | P15692 | 1/20 | 0.48 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.48 |
| ▸ | LGALS3 | P17931 | 2/20 | 0.48 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.48 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.48 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.47 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.47 |
| ▸ | LGALS7; LGALS7B | P47929 | 1/20 | 0.47 |
| ▸ | IGF2R | P11717 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cellobiose SCHEMBL9109171 | 0.90 | TYR (0.45) | CA12CA1CA2CA9CA14 | |
| SCHEMBL20677306 | 0.88 | LGALS3 (0.47) | CA12CA1CA2CA9CA14 | |
| Cellobiose SCHEMBL19951548 | 0.86 | LGALS3 (0.54) | CA12CA1CA2CA9AMY2A | |
| Maltotriose SCHEMBL28087482 | 0.85 | LGALS3 (0.53) | CA12CA1CA2CA9AMY2A | |
| Cellobiose SCHEMBL5054467 | 0.85 | LGALS3 (0.53) | AMY2AFGF1FGF2VEGFAHPSE | |
| Cellobiose SCHEMBL24662526 | 0.85 | LGALS8 (0.61) | AMY2ATYRLGALS3LGALS8LGALS4 | |
| Cellobiose SCHEMBL23752618 | 0.85 | LGALS8 (0.61) | AMY2ATYRLGALS3LGALS8LGALS4 | |
| Cellobiose SCHEMBL24202679 | 0.85 | LGALS8 (0.61) | AMY2ATYRLGALS3LGALS8LGALS4 | |
| Cellobiose SCHEMBL23708014 | 0.85 | LGALS8 (0.61) | AMY2ATYRLGALS3LGALS8LGALS4 | |
| Cellobiose SCHEMBL21114355 | 0.85 | LGALS8 (0.61) | AMY2ATYRLGALS3LGALS8LGALS4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3433374-A1 | GLYCOSYLATED MONO(2-HYDROXYETHYL) TEREPHTHALIC ACID AND GLYCOSYLATED BIS(2-HYDROXYETHYL) TEREPHTHALIC ACID | Julius-Maximilians-Universitaet Wuerzburg (DE) | 2019-01-30 | — | — | EP | disclosed |