Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR5 | Q9H228 | 7/20 | 0.58 |
| ▸ | MAOB | P27338 | 3/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 5/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL30828821 | 0.89 | S1PR5 (0.69) | S1PR5MAOBMCL1KCNA5SCN5A | |
| Trifluoroacetic Acid SCHEMBL20573650 | 0.89 | S1PR5 (0.69) | S1PR5MAOBMCL1KCNA5SCN5A | |
| SCHEMBL19201090 | 0.75 | S1PR5 (0.82) | S1PR5MAOBMCL1 | |
| SCHEMBL30828825 | 0.74 | S1PR5 (1.00) | S1PR5MAOBMCL1KCNA5SCN5A | |
| SCHEMBL19201148 | 0.74 | S1PR5 (1.00) | S1PR5MAOBMCL1KCNA5SCN5A | |
| SCHEMBL20679855 | 0.71 | MEN1 (0.33) | S1PR5 | |
| SCHEMBL20573455 | 0.64 | S1PR5 (0.73) | S1PR5MAOBMCL1KCNA5SCN5A | |
| SCHEMBL29332504 | 0.63 | S1PR5 (0.74) | S1PR5MCL1 | |
| Trifluoroacetic Acid SCHEMBL20679856 | 0.63 | OPRM1 (0.35) | S1PR5 | |
| SCHEMBL20573391 | 0.62 | S1PR5 (0.68) | S1PR5MAOBMCL1KCNA5SCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10730830-B2 | Tetrahydronaphthalene derivative | ONO PHARMACEUTICAL CO., LTD. (JP) | 2020-08-04 | — | — | US | disclosed |
| US-20190031605-A1 | TETRAHYDRONAPHTHALENE DERIVATIVE | ONO PHARMACEUTICAL CO., LTD. (JP) | 2019-01-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10730830-B2 | Tetrahydronaphthalene derivative | S1PR5, S1PR1, GPR55 | S1PR5 1/4885MAOB 2194/4885MCL1 2364/4885 |
| US-20190031605-A1 | TETRAHYDRONAPHTHALENE DERIVATIVE | S1PR5, S1PR1, GPR55 | S1PR5 1/4885MAOB 2063/4885MCL1 2223/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.