SCHEMBL20680488

SCHEMBL20680488

CC(=O)O[SiH](OC(C)=O)OC(C)=O.[SiH4]

nearest known ligand 0.41

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.41
TSHR P16473 3/20 0.41
LMNA P02545 3/20 0.33
HSD17B10 Q99714 2/20 0.33
TDP1 Q9NUW8 1/20 0.33
THPO P40225 1/20 0.31
FFAR3 O14843 1/20 0.31
LCK P06239 1/20 0.31
FYN P06241 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL203518 0.96 ALDH1A1 (0.44) ALDH1A1TSHRLMNAHSD17B10TDP1
Fluoromethane SCHEMBL28191693 0.90 ALDH1A1 (0.39) ALDH1A1TSHRLMNAHSD17B10TDP1
Ethylene SCHEMBL27488666 0.90 ALDH1A1 (0.39) ALDH1A1TSHRLMNAHSD17B10TDP1
Tetramethylammonium Ion SCHEMBL5398916 0.87 ALDH1A1 (0.37) ALDH1A1TSHRLMNAHSD17B10TDP1
Trimethylammonium SCHEMBL5391194 0.87 ALDH1A1 (0.37) ALDH1A1TSHRLMNAHSD17B10TDP1
Dimethylamine SCHEMBL5389239 0.87 ALDH1A1 (0.44) ALDH1A1TSHRLMNAHSD17B10TDP1
SCHEMBL28253061 0.82 ALDH1A1 (0.39) ALDH1A1TSHRLMNAHSD17B10TDP1
SCHEMBL9753183 0.80
SCHEMBL9007767 0.80 ALDH1A1 (0.44) ALDH1A1TSHRLMNAHSD17B10TDP1
Methacrylic Acid SCHEMBL28675559 0.80 TDP1 (0.38) ALDH1A1TSHRHSD17B10TDP1FFAR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019020770-A1 ORGANOSILICON COMPOUNDS AND COMPOSITIONS DITECPESA, S.A. (ES) 2019-01-31 WO disclosed