SCHEMBL2068153

SCHEMBL2068153

NS(=O)(=O)c1c(Cl)nc2cccnn12

nearest known ligand 0.36

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PDE4A P27815 16/20 0.36
PDE4B Q07343 15/20 0.36
PDE4C Q08493 15/20 0.36
PDE4D Q08499 15/20 0.36
CA1 P00915 2/20 0.36
CA2 P00918 2/20 0.36
CA9 Q16790 2/20 0.36
MAPK1 P28482 1/20 0.36
CA12 O43570 1/20 0.36
KDM4E B2RXH2 1/20 0.35
MAPT P10636 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
PDE10A Q9Y233 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2067978 0.85 PDE4A (0.36) PDE4APDE4BPDE4CPDE4DKDM4E
SCHEMBL2066471 0.81 PDE4A (0.40) PDE4APDE4BPDE4CPDE4DCA1
SCHEMBL2066630 0.81 CA1 (0.36) PDE4APDE4BPDE4CPDE4DCA1
SCHEMBL2065831 0.81 CA1 (0.36) PDE4APDE4BPDE4CPDE4DCA1
SCHEMBL2065529 0.77 PDE4A (0.43) PDE4APDE4BPDE4CPDE4D
SCHEMBL2066052 0.77 PDE4A (0.33) PDE4APDE4BPDE4CPDE4DCA1
SCHEMBL2065638 0.77 PDE4A (0.37) PDE4APDE4BPDE4CPDE4DCA1
SCHEMBL2066954 0.77 PDE4A (0.40) PDE4APDE4BPDE4CPDE4DCA1
SCHEMBL2066982 0.76 PDE4A (0.39) PDE4APDE4BPDE4CPDE4DCA1
SCHEMBL3157242 0.75 TNF (0.54) KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8399381-B2 Condensed heterocyclic sulfonyl urea compound, a herbicide containing the same, and a method for weed control using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-03-19 US disclosed
US-8148524-B2 Process for producing sulfonyl chloride compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-04-03 US disclosed
EP-1932846-B1 METHOD FOR PRODUCING SULFONYL CHLORIDE COMPOUND SUMITOMO CHEMICAL CO (JP) 2010-10-27 EP disclosed
US-20090247748-A1 PROCESS FOR PRODUCING SULFONYL CHLORIDE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-10-01 US disclosed
EP-1932846-A1 METHOD FOR PRODUCING SULFONYL CHLORIDE COMPOUND Sumitomo Chemical Company, Limited (JP) 2008-06-18 EP disclosed
US-7307165-B2 Process for producting imidazo[1,2-b]pyridazine derivative SUMITOMO CHEMICAL TAKEDA AGRO COMPANY, LIMITED (JP) 2007-12-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090247748-A1 PROCESS FOR PRODUCING SULFONYL CHLORIDE COMPOUND SALL4, CLCN2, CLIC1 PDE4A 4317/4885PDE4B 4162/4885PDE4C 4481/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.