SCHEMBL2065831

SCHEMBL2065831

NS(=O)(=O)c1c(F)nc2cccnn12

nearest known ligand 0.36

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.36
CA2 P00918 2/20 0.36
CA9 Q16790 2/20 0.36
MAPK1 P28482 1/20 0.36
CA12 O43570 1/20 0.36
PDE4A P27815 14/20 0.34
PDE4B Q07343 15/20 0.33
PDE4D Q08499 15/20 0.33
PDE4C Q08493 14/20 0.33
PTGS1 P23219 1/20 0.33
KLK7 P49862 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2067969 0.84 PDE4B (0.35) PDE4APDE4BPDE4DPDE4C
SCHEMBL2066471 0.81 PDE4A (0.40) CA1CA2CA9MAPK1CA12
SCHEMBL2068153 0.81 PDE4A (0.36) CA1CA2CA9MAPK1CA12
SCHEMBL2066630 0.81 CA1 (0.36) CA1CA2CA9MAPK1CA12
SCHEMBL2065529 0.77 PDE4A (0.43) PDE4APDE4BPDE4DPDE4C
SCHEMBL2065638 0.77 PDE4A (0.37) CA1CA2CA9MAPK1CA12
SCHEMBL2066954 0.77 PDE4A (0.40) CA1CA2CA9MAPK1CA12
SCHEMBL2066052 0.77 PDE4A (0.33) CA1CA2CA9MAPK1CA12
SCHEMBL2066982 0.76 PDE4A (0.39) CA1CA2CA9MAPK1CA12
SCHEMBL2065708 0.75 PDE4A (0.39) CA1CA2CA9MAPK1CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8148524-B2 Process for producing sulfonyl chloride compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-04-03 US disclosed
EP-1932846-B1 METHOD FOR PRODUCING SULFONYL CHLORIDE COMPOUND SUMITOMO CHEMICAL CO (JP) 2010-10-27 EP disclosed
US-20090247748-A1 PROCESS FOR PRODUCING SULFONYL CHLORIDE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-10-01 US disclosed
EP-1932846-A1 METHOD FOR PRODUCING SULFONYL CHLORIDE COMPOUND Sumitomo Chemical Company, Limited (JP) 2008-06-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090247748-A1 PROCESS FOR PRODUCING SULFONYL CHLORIDE COMPOUND SALL4, CLCN2, CLIC1 CA1 1402/4885CA2 176/4885CA9 760/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.