Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ARG1 | P05089 | 11/20 | 0.60 |
| ▸ | ARG2 | P78540 | 11/20 | 0.60 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | ME2 | P23368 | 1/20 | 0.43 |
| ▸ | ME1 | P48163 | 1/20 | 0.43 |
| ▸ | ME3 | Q16798 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GPR183 | P32249 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20683394 | 0.89 | ARG1 (0.47) | ARG1ARG2ME2ME1ME3 | |
| SCHEMBL893860 | 0.88 | ARG1 (0.77) | ARG1ARG2 | |
| Hydrochloric Acid SCHEMBL894576 | 0.87 | ARG1 (0.76) | ARG1ARG2 | |
| SCHEMBL20683397 | 0.85 | ARG1 (0.58) | ARG1ARG2MEN1KMT2A | |
| SCHEMBL20683417 | 0.84 | ARG1 (0.65) | ARG1ARG2CYP2C19 | |
| SCHEMBL20683503 | 0.83 | ARG1 (0.79) | ARG1ARG2KMT2A | |
| SCHEMBL20683518 | 0.78 | ARG1 (0.51) | ARG1ARG2 | |
| SCHEMBL20683412 | 0.78 | ARG1 (0.52) | ARG1ARG2MEN1KMT2A | |
| SCHEMBL18323834 | 0.78 | ARG1 (0.79) | ARG1ARG2MEN1KMT2A | |
| SCHEMBL894833 | 0.78 | ARG1 (0.62) | ARG1ARG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2560978-B1 | INHIBITORS OF ARGINASE AND THEIR THERAPEUTIC APPLICATIONS | MARS INC (US) | 2019-01-30 | — | — | EP | disclosed |