Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ARG1 | P05089 | 10/20 | 0.58 |
| ▸ | ARG2 | P78540 | 10/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | MGLL | Q99685 | 7/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL895432 | 0.88 | ARG1 (0.74) | ARG1ARG2MAPTMGLL | |
| Hydrochloric Acid SCHEMBL895384 | 0.87 | ARG1 (0.73) | ARG1ARG2MAPTMGLL | |
| SCHEMBL20683402 | 0.85 | ARG1 (0.60) | ARG1ARG2MEN1KMT2A | |
| SCHEMBL20683503 | 0.84 | ARG1 (0.79) | ARG1ARG2MAPTKMT2A | |
| SCHEMBL20683417 | 0.83 | ARG1 (0.65) | ARG1ARG2ALDH1A1 | |
| SCHEMBL20683518 | 0.79 | ARG1 (0.51) | ARG1ARG2MAPT | |
| SCHEMBL895148 | 0.77 | ARG1 (0.69) | ARG1ARG2 | |
| SCHEMBL20683534 | 0.77 | ARG1 (0.50) | ARG1ARG2MAPT | |
| Hydrochloric Acid SCHEMBL894453 | 0.76 | ARG1 (0.68) | ARG1ARG2 | |
| SCHEMBL20683443 | 0.75 | ARG1 (0.63) | ARG1ARG2MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2560978-B1 | INHIBITORS OF ARGINASE AND THEIR THERAPEUTIC APPLICATIONS | MARS INC (US) | 2019-01-30 | — | — | EP | disclosed |