Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ARG1 | P05089 | 16/20 | 0.71 |
| ▸ | ARG2 | P78540 | 16/20 | 0.71 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20683468 | 0.90 | ARG1 (0.58) | ARG1ARG2 | |
| SCHEMBL20683435 | 0.89 | ARG1 (0.72) | ARG1ARG2 | |
| SCHEMBL20683448 | 0.89 | ARG1 (0.73) | ARG1ARG2MEN1KMT2AALDH1A1 | |
| SCHEMBL20683421 | 0.88 | ARG1 (0.58) | ARG1ARG2ALDH1A1 | |
| SCHEMBL20683441 | 0.86 | ARG1 (0.74) | ARG1ARG2MEN1KMT2AALDH1A1 | |
| SCHEMBL20683477 | 0.85 | ARG1 (0.53) | ARG1ARG2ALDH1A1 | |
| SCHEMBL20683475 | 0.84 | ARG1 (0.56) | ARG1ARG2MEN1KMT2A | |
| SCHEMBL894945 | 0.83 | ARG1 (1.00) | ARG1ARG2 | |
| SCHEMBL20683450 | 0.82 | ARG1 (0.57) | ARG1ARG2MEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL894272 | 0.82 | ARG1 (0.98) | ARG1ARG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2560978-B1 | INHIBITORS OF ARGINASE AND THEIR THERAPEUTIC APPLICATIONS | MARS INC (US) | 2019-01-30 | — | — | EP | disclosed |