Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ARG1 | P05089 | 8/20 | 0.74 |
| ▸ | ARG2 | P78540 | 8/20 | 0.74 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20683485 | 0.86 | ARG1 (0.71) | ARG1ARG2MEN1KMT2AALDH1A1 | |
| SCHEMBL895504 | 0.85 | ARG1 (1.00) | ARG1ARG2 | |
| Hydrochloric Acid SCHEMBL894097 | 0.84 | ARG1 (0.98) | ARG1ARG2 | |
| SCHEMBL20683458 | 0.84 | ARG1 (0.53) | ARG1ARG2MEN1KMT2A | |
| SCHEMBL20683448 | 0.82 | ARG1 (0.73) | ARG1ARG2MEN1KMT2AKDM4E | |
| SCHEMBL20683435 | 0.80 | ARG1 (0.72) | ARG1ARG2 | |
| SCHEMBL20683468 | 0.78 | ARG1 (0.58) | ARG1ARG2 | |
| SCHEMBL20683449 | 0.77 | ACHE (0.52) | ARG1ARG2MEN1KMT2A | |
| SCHEMBL10207114 | 0.77 | ARG1 (0.59) | ARG1ARG2MEN1KMT2ACYP2A13 | |
| SCHEMBL20683421 | 0.77 | ARG1 (0.58) | ARG1ARG2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2560978-B1 | INHIBITORS OF ARGINASE AND THEIR THERAPEUTIC APPLICATIONS | MARS INC (US) | 2019-01-30 | — | — | EP | disclosed |