Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ARG1 | P05089 | 13/20 | 0.81 |
| ▸ | ARG2 | P78540 | 13/20 | 0.81 |
| ▸ | ACLY | P53396 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12292594 | 0.95 | ARG1 (0.81) | ARG1ARG2ACLYSIGMAR1 | |
| SCHEMBL895655 | 0.89 | ARG1 (1.00) | ARG1ARG2 | |
| SCHEMBL30169803 | 0.89 | ARG1 (1.00) | ARG1ARG2 | |
| SCHEMBL895249 | 0.85 | ARG1 (1.00) | ARG1ARG2 | |
| SCHEMBL30169937 | 0.85 | ARG1 (1.00) | ARG1ARG2 | |
| Hydrochloric Acid SCHEMBL894665 | 0.84 | ARG1 (0.98) | ARG1ARG2 | |
| SCHEMBL20683404 | 0.80 | ARG1 (0.61) | ARG1ARG2SIGMAR1 | |
| SCHEMBL895504 | 0.79 | ARG1 (1.00) | ARG1ARG2 | |
| SCHEMBL20683512 | 0.79 | ARG1 (0.53) | ARG1ARG2SIGMAR1 | |
| Hydrochloric Acid SCHEMBL894097 | 0.78 | ARG1 (0.98) | ARG1ARG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2560978-B1 | INHIBITORS OF ARGINASE AND THEIR THERAPEUTIC APPLICATIONS | MARS INC (US) | 2019-01-30 | — | — | EP | disclosed |