Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Ethylenediamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | CA12 | O43570 | 4/20 | 0.40 |
| ▸ | CA6 | P23280 | 4/20 | 0.40 |
| ▸ | CA7 | P43166 | 4/20 | 0.40 |
| ▸ | CA9 | Q16790 | 4/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | CA3 | P07451 | 3/20 | 0.40 |
| ▸ | CA4 | P22748 | 3/20 | 0.40 |
| ▸ | CA5A | P35218 | 3/20 | 0.40 |
| ▸ | BLM | P54132 | 2/20 | 0.40 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylenediamine SCHEMBL3650340 | 1.00 | — | — | |
| Ethylenediamine SCHEMBL11163220 | 1.00 | NFKB1 (0.44) | NFKB1TSHRCA12CA6CA7 | |
| Ethylenediamine SCHEMBL1557999 | 1.00 | — | — | |
| Ethylenediamine SCHEMBL580102 | 1.00 | — | — | |
| Ethylenediamine SCHEMBL3505481 | 1.00 | — | — | |
| Ethylenediamine SCHEMBL11165159 | 1.00 | NFKB1 (0.44) | NFKB1TSHRCA12CA6CA7 | |
| Ethylenediamine SCHEMBL11158606 | 1.00 | NFKB1 (0.44) | NFKB1TSHRCA12CA6CA7 | |
| Ethylenediamine SCHEMBL2884523 | 0.93 | — | — | |
| Ethylenediamine SCHEMBL8718969 | 0.93 | NFKB1 (0.40) | NFKB1TSHRCA12CA6CA7 | |
| Ethylenediamine SCHEMBL7775525 | 0.93 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107207878-A | Curable compositions and film | 富士胶片制造欧洲有限公司 | 2017-09-26 | — | — | CN | claimed |
| WO-2024143488-A1 | SENSOR ELEMENT, SENSOR ELEMENT MANUFACTURING METHOD, AND GAS MEASURING DEVICE | TDK株式会社 | 2024-07-04 | — | — | WO | disclosed |
| CN-116656118-A | Organic polyurethane chemical grouting material, components, preparation method and application | 河北同成科技股份有限公司 | 2023-08-29 | — | — | CN | disclosed |
| CN-116162434-A | Epoxy modified low-VOC (volatile organic compound) double-component polyurethane adhesive and preparation method thereof | 烟台德邦科技股份有限公司 | 2023-05-26 | — | — | CN | disclosed |
| CN-115379823-A | Cosmeceutical composition | 俄亥俄州立创新基金会 | 2022-11-22 | — | — | CN | disclosed |
| CN-110256348-B | Synthetic method of rubber vulcanizing agent DTDC | 山东阳谷华泰化工股份有限公司 | 2022-08-12 | — | — | CN | disclosed |
| CN-111004083-B | Method for purifying alkene organic compound | 江苏广域化学有限公司 | 2022-05-10 | — | — | CN | disclosed |
| CN-111004083-A | Method for purifying alkene organic compound | 江苏广域化学有限公司 | 2020-04-14 | — | — | CN | disclosed |
| CN-110256348-A | A kind of synthetic method of vulcanizer DTDC | 山东阳谷华泰化工股份有限公司 | 2019-09-20 | — | — | CN | disclosed |
| EP-1853356-B1 | CONFORMAL FILTER CARTRIDGES AND METHODS | 3M INNOVATIVE PROPERTIES CO (US) | 2018-04-25 | — | — | EP | disclosed |
| US-20050155665-A1 | Respirator filter canisters and method of filling same | AVON PROTECTION SYSTEMS, INC. | 2005-07-21 | — | — | US | disclosed |
| WO-2005065280-A2 | REPAIR OF SPNAL ANNULAR DEFECTS AND ANNULO-NUCLEOPLASTY REGENERATION | BIOMERIX CORPORATION (US) | 2005-07-21 | — | — | WO | disclosed |
| US-20050043816-A1 | Reticulated elastomeric matrices, their manufacture and use in implantable devices | DSM IP ASSETS B.V. (NL) | 2005-02-24 | — | — | US | disclosed |
| EP-1499396-A1 | GAS MASK FILTER CANISTER | Avon Protection Systems, Inc. (US) | 2005-01-26 | — | — | EP | disclosed |
| EP-1496996-A1 | RESPIRATOR FILTER CANISTERS AND METHOD OF FILLING SAME | Avon Protection Systems, Inc. (US) | 2005-01-19 | — | — | EP | disclosed |
| WO-2004103208-A2 | MANUFACTURE AND USE OF IMPLANTABLE RETICULATED ELASTOMERIC MATRICES | BIOMERIX CORPORATION (US) | 2004-12-02 | — | — | WO | disclosed |
| WO-2003090872-A1 | RESPIRATOR FILTER CANISTERS AND METHOD OF FILLING SAME | AVON PROTECTION SYSTEMS, INC. (US) | 2003-11-06 | — | — | WO | disclosed |
| WO-2003090873-A1 | GAS MASK FILTER CANISTER | AVON PROTECTION SYSTEMS, INC. (US) | 2003-11-06 | — | — | WO | disclosed |
| US-6045741-A | POLYOL CONTAINING A HYDROPHILIC ORGANIC ACID METAL SALT AND/OR A POLYMER THEREOF IS USED AS THE POLYOL. THE POLYURETHANE FOAM IS THE POLYURETHANE FOAM IS COMPRESSED TO A THICKNESS OF 5 TO 80% OF ITS INITIAL THICKNESS. | BRIDGESTONE CORPORATION (JP) | 2000-04-04 | — | — | US | disclosed |
| US-4309511-A | COBALT COMPOUND, COPPER COMPOUND, AND HETEROCYCLIC AMINE | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1982-01-05 | — | — | US | disclosed |