Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Ethylenediamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | CA12 | O43570 | 3/20 | 0.36 |
| ▸ | CA6 | P23280 | 3/20 | 0.36 |
| ▸ | CA7 | P43166 | 3/20 | 0.36 |
| ▸ | CA9 | Q16790 | 3/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA3 | P07451 | 2/20 | 0.36 |
| ▸ | CA4 | P22748 | 2/20 | 0.36 |
| ▸ | CA5A | P35218 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | BLM | P54132 | 2/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylenediamine SCHEMBL6910153 | 0.93 | — | — | |
| Ethylenediamine SCHEMBL16767515 | 0.93 | — | — | |
| Ethylenediamine SCHEMBL3699159 | 0.93 | NFKB1 (0.44) | NFKB1TSHRCA12CA6CA7 | |
| Ethylenediamine SCHEMBL11228367 | 0.93 | — | — | |
| Ethylenediamine SCHEMBL11158606 | 0.93 | NFKB1 (0.44) | NFKB1TSHRCA12CA6CA7 | |
| Ethylenediamine SCHEMBL3505481 | 0.93 | — | — | |
| Ethylenediamine SCHEMBL3650340 | 0.93 | — | — | |
| Ethylenediamine SCHEMBL580102 | 0.93 | — | — | |
| Ethylenediamine SCHEMBL206845 | 0.93 | NFKB1 (0.44) | NFKB1TSHRCA12CA6CA7 | |
| Ethylenediamine SCHEMBL11163220 | 0.93 | NFKB1 (0.44) | NFKB1TSHRCA12CA6CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0827961-A1 | PROCESS FOR THE PREPARATION OF BETA-LACTAM COMPOUNDS | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1998-03-11 | — | — | EP | disclosed |