Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F13A1 | P00488 | 2/20 | 0.42 |
| ▸ | TGM2 | P21980 | 2/20 | 0.42 |
| ▸ | TGM1 | P22735 | 2/20 | 0.42 |
| ▸ | CCNK | O75909 | 1/20 | 0.40 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.40 |
| ▸ | TBK1 | Q9UHD2 | 9/20 | 0.40 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18291489 | 0.80 | CHRM2 (0.46) | CCNKCDK12TBK1CHRM2CHRM4 | |
| SCHEMBL28705806 | 0.79 | GPR119 (0.54) | CCNKCDK12CHRM2CHRM4CHRM1 | |
| SCHEMBL30521135 | 0.79 | GPR119 (0.54) | CCNKCDK12CHRM2CHRM4CHRM1 | |
| SCHEMBL18083762 | 0.76 | RXFP1 (0.45) | CCNKCDK12ACKR3CHRM2CHRM4 | |
| SCHEMBL20160543 | 0.75 | TP53 (0.48) | CCNKCDK12CHRM2CHRM4CHRM1 | |
| SCHEMBL4065096 | 0.75 | WNT3A (0.55) | F13A1TGM2TGM1CCNKDDB1 | |
| SCHEMBL20788464 | 0.74 | VEGFA (0.53) | CHRM2CHRM4CHRM1CHRM3GPR119 | |
| SCHEMBL20684949 | 0.74 | VEGFA (0.50) | F13A1TGM2TGM1CHRM2CHRM4 | |
| SCHEMBL12367628 | 0.74 | KDM4E (0.45) | CCNKCDK12CHRM2CHRM4CHRM1 | |
| SCHEMBL24696026 | 0.73 | CHRM2 (0.47) | TBK1ACKR3CHRM2CHRM4CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3271348-B1 | NEW FYN KINASE INHIBITORS | Rottapharm Biotech Srl (IT) | 2019-01-30 | — | — | EP | disclosed |