Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | KIF11 | P52732 | 3/20 | 0.55 |
| ▸ | ACHE | P22303 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | CHUK | O15111 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2760335 | 0.90 | KIF11 (0.64) | LMNAKIF11ACHEGAAHPGD | |
| SCHEMBL345690 | 0.87 | KIF11 (0.67) | LMNAKIF11ACHEGAAHPGD | |
| SCHEMBL29362354 | 0.87 | KIF11 (0.67) | LMNAKIF11ACHEGAAHPGD | |
| SCHEMBL607827 | 0.87 | CHUK (0.64) | LMNAGAAHPGDCYP1A2MEN1 | |
| SCHEMBL29453525 | 0.87 | CHUK (0.64) | LMNAGAAHPGDCYP1A2MEN1 | |
| SCHEMBL14095141 | 0.86 | MEN1 (0.63) | LMNAGAAHPGDCYP1A2MEN1 | |
| SCHEMBL13828021 | 0.82 | KIF11 (0.62) | LMNAKIF11ACHEGAAHPGD | |
| SCHEMBL550449 | 0.82 | CHUK (0.60) | LMNAGAAHPGDCYP1A2MEN1 | |
| SCHEMBL25583633 | 0.81 | MEN1 (0.56) | LMNAKIF11GAAHPGDCYP1A2 | |
| SCHEMBL6009586 | 0.79 | KIF11 (0.62) | LMNAKIF11ALDH1A1MAPTRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3347355-B1 | HETEROTRICYCLIC SULFONAMIDES AS ANTI-CANCER AGENTS | ICAHN SCHOOL MED MOUNT SINAI (US) | 2022-07-13 | — | — | EP | disclosed |
| EP-2943480-B1 | PIPERIDINYLCARBAZOLE AS ANTIMALARIAL | MERCK PATENT GMBH (DE) | 2019-01-30 | — | — | EP | disclosed |