Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHUK | O15111 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | AHR | P35869 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.51 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.51 |
| ▸ | C5 | P01031 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.51 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29453525 | 0.95 | CHUK (0.64) | CHUKLMNAHPGDCYP1A2GAA | |
| SCHEMBL607827 | 0.95 | CHUK (0.64) | CHUKLMNAHPGDCYP1A2GAA | |
| SCHEMBL29354683 | 0.87 | LMNA (0.56) | CHUKLMNAHPGDCYP1A2GAA | |
| SCHEMBL29586622 | 0.87 | LMNA (0.56) | CHUKLMNAHPGDCYP1A2GAA | |
| SCHEMBL276018 | 0.87 | LMNA (0.56) | CHUKLMNAHPGDCYP1A2GAA | |
| SCHEMBL2141394 | 0.85 | PARP1 (0.61) | CHUKLMNAAHRHPGDMEN1 | |
| SCHEMBL29643218 | 0.84 | AHR (0.64) | CHUKLMNAAHRHPGDMEN1 | |
| SCHEMBL29993295 | 0.84 | AHR (0.64) | CHUKLMNAAHRHPGDMEN1 | |
| SCHEMBL607394 | 0.84 | AHR (0.64) | CHUKLMNAAHRHPGDMEN1 | |
| SCHEMBL21448352 | 0.83 | MEN1 (0.51) | CHUKLMNAAHRHPGDCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140088313-A1 | SUBSTITUTED INDOLOCARBAZOLES | XEROX CORPORATION (US) | 2014-03-27 | — | — | US | disclosed |
| US-8609867-B2 | Substituted indolocarbazoles | XEROX CORPORATION (US) | 2013-12-17 | — | — | US | disclosed |
| US-20120157689-A1 | SUBSTITUTED INDOLOCARBAZOLES | XEROX CORPORATION (US) | 2012-06-21 | — | — | US | disclosed |
| US-8110690-B2 | Substituted indolocarbazoles | XEROX CORPORATION (US) | 2012-02-07 | — | — | US | disclosed |
| US-20090036689-A1 | SUBSTITUTED INDOLOCARBAZOLES | XEROX CORPORATION (US) | 2009-02-05 | — | — | US | disclosed |
| US-7456424-B2 | Thin film transistors including indolocarbozoles | XEROX CORPORATION (US) | 2008-11-25 | — | — | US | disclosed |
| US-20060124923-A1 | Thin film transistors including indolocarbazoles | XEROX CORPORATION | 2006-06-15 | — | — | US | disclosed |
| US-20060125009-A1 | Thin film transistors including indolocarbazoles | XEROX CORPORATION | 2006-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090036689-A1 | SUBSTITUTED INDOLOCARBAZOLES | HTR3C, HTR3A, AANAT | CHUK 1758/4885LMNA 3353/4885AHR 41/4885 |
| US-20120157689-A1 | SUBSTITUTED INDOLOCARBAZOLES | HTR3C, HTR3A, AANAT | CHUK 1758/4885LMNA 3353/4885AHR 41/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.